The assessment of left ventricular volume and function in gated small animal F-FDG PET/CT imaging: a comparative study of three commercially available software tools.

Background: Several software tools have been developed for gated PET imaging that use distinct algorithms to analyze tracer uptake, myocardial perfusion, and left ventricle volumes and function. Studies suggest that different software tools cannot be used interchangeably in humans. In this study, we sought to compare the left ventricular parameters in gated F-FDG PET/CT imaging in mice by three commercially available software tools: PMOD, MIM, and QGS.