[COPD inhaled therapy narrative review].

The basis of COPD maintenance treatment is the long-acting bronchodilators and the inhaled corticosteroids. Faced with the recent modifications in the clinical practice guidelines, we have carried out a review of studies that contrast the various therapeutic alternatives and pharmacological agents within each category, with the fundamental purpose of shedding light on which of these options prove to be more effective. Triple therapy stands out as essential in poorly controlled patients or with an eosinophilic phenotype, surpassing dual therapy.

Sciatica. Management for family physicians.

Sciatica or lower back pain with sciatic radiation is a frequent medical problem in primary care. The aim of this article is to better inform medical practitioners on diagnosis and management of lower back pain with sciatic radiation. Updated information on sciatica management is important for family physicians.

Migraine review for general practice.

Migraine continues second among the world's causes of disability. Diagnosis is based on the history and clinical examination and imaging is usually not necessary. Migraine can be subdivided depending on whether there is an aura or not and based on the frequency of the headaches.

[COPD inhaled therapy narrative review].

Inhaled therapy with long-acting bronchodilators is the base of pharmacological treatment in COPD. In order to find out those that offer better control, a search was carried out in Medline (Pubmed). Comparative studies of inhaler therapy in COPD patients were analyzed.

Rapid antigen tests for the detection of SARS-CoV-2: A narrative review.

The rapid identificationand isolation of COVID-19 patients has become the cornerstone for the control of the recent outbreak. Real-time quantitative polymerase chain reaction is routinely used to confirm COVID-19 diagnosis and is considered the gold standard due to high sensitivity and specificity. Nevertheless, it usually takes several days and a relatively higher cost.

Vitamin D, the natural way.

Background & Aims: Vitamin D is a fat-soluble vitamin whose main function in the body is the regulation of bone mineral metabolism. In the last two decades, there has been an intensive research for possible vitamin D benefits in non-skeletal health but as today it still remains unclear. The aim of this article is to review vitamin D metabolism and the natural sources to encourage lifestyle changes to avoid deficiency.

[Vitamin D for daily practice].

Vitamin D is a fat-soluble vitamin which has the regulation of calcium-phosphorus metabolism in the body as its main function. Vitamin D receptor is present in most of the nucleated cells of the body, and its role in multiple body processes is being discovered. The 3 main sources of vitamin D are ultraviolet sun radiation, diet, and supplementation.

COPD from an everyday primary care point of view.

Introduction: The purpose of this study is to use real world evidence on treatment use to evaluate drug superiority within the same treatment group.

Methods: Retrospective cohort analysis using the Spanish Database for Pharmacoepidemiological Research in Primary Care (BIFAP). Data includes longitudinal routine clinical data extracted from practice records of 7,890,485 patients.

[Importance of selective immunoglobulin A deficiency].

Selective IgA deficiency is the most common primary immunodeficiency. Little is known about the pathogenetic mechanisms leading to this disease. It is estimated that the incidence of this disease in Spain is 1:163.

[A 45 year-old male with lumbar tumours].

A 45 year old Filipino male, with history of Hepatitis B virus infection, was seen in his primary care clinic with a lumbar mass for the past three months. On physical examination the lower limbs showed decrease strength, chest X-rays showed bilateral thickening of the apical pleura, the Mantoux skin test was positive and a lumbar magnetic resonance imaging study showed a compression fracture of D4 vertebral body and soft-tissue abscess in L1. Microbiological examination was positive for M.

[Colorectal interval cancer and colonoscopy quality criteria: presentation of a case].

We present the case of a 63 year-old woman without any family cancer background, who after having properly followed the cancer screening program for mild risk population, was diagnosed with colorectal cancer (stage IV) 3 years after a clear colonoscopy. This entity is known as interval colorectal cancer (diagnosed between correct screening periods). The colorectal cancer screening strategies and the specialized multidisciplinary units are experiencing important changes.

[A case of upper extremity deep vein thrombosis].

The case is presented of a 41 year-old women with a personal history of smoking and treated with oral contraceptives, who began taking analgesics and muscle relaxants due to a right cervical pain. As her clinical condition did not improve she was seen again. During the physical examination an increase of soft tissue in the right supraclavicular area was observed.