Improving serum redox balance, inflammatory status, physical function, and cognitive ability through dual-task resistance training and detraining in nursing home residents.

Objective: This study investigated the effects of dual-task resistance training (RT) and detraining on physical function, cognitive capacity, lipid profile, renal function, oxidative stress markers, and chronic inflammation of institutionalized older adults.

Methods: The study involved 11 older adults (83.09 ± 8.

Developing and validation of a smartphone app for post-discharge early follow-up after colorectal cancer surgeries.

Background: Colorectal surgeries are complex procedures associated with high rates of complications and hospital readmission.

Objective: This study aimed to develop an electronic post-discharge follow-up plan to remotely monitor patients' symptoms in the postoperative period of colorectal surgeries and evaluate the outcomes of emergency department visits and the rate of severe complications within 15 days after hospital discharge.

Design: We developed a digital tool capable of remotely assessing symptoms that could indicate complications related to colorectal surgical procedures and directing early management.

Rifabutin: a repurposed antibiotic with high potential against planktonic and biofilm staphylococcal clinical isolates.

poses a significant threat as an opportunistic pathogen in humans, and animal medicine, particularly in the context of hospital-acquired infections (HAIs). Effective treatment is a significant challenge, contributing substantially to the global health burden. While antibiotic therapy remains the primary approach for staphylococcal infections, its efficacy is often compromised by the emergence of resistant strains and biofilm formation.

Germline DNA Damage Repair Gene Alterations in Patients with Metachronous Breast and Colorectal Cancer.

A hereditary component of breast (BC) and colorectal cancer (CRC) has been described in approximately one-third of these tumor types. BC patients have an increased risk of developing CRC as a second primary tumor and vice versa. Germline genomic variants (NextSeq550, Illumina) were investigated in 24 unrelated BC and/or CRC patients and 7 relatives from 3 index patients.

Impact of the Early Phase of the COVID-19 Pandemic on the Quality of Care for Colorectal and Anal Cancers at Comprehensive Cancer Centers on Two Continents.

Purpose: The early phase of the COVID-19 pandemic affected cancer care globally. Evaluating the impact of the pandemic on the quality of cancer care delivery is crucial for understanding how changes in care delivery may influence outcomes. Our study compared care delivered during the early phase of the pandemic with the same period in the previous year at two institutions across continents (Princess Margaret Cancer Center [PM] in Canada and A.

Light-Intensity Physical Activity and Sedentary Behavior Are Associated With Blood Pressure Levels in Adolescents.

Purpose: To investigate the associations between physical activity (PA) intensities, sedentary behavior (SB), and blood pressure (BP) in adolescents, according to sex.

Method: This cross-sectional study involved 95 male and female adolescents aged 15-18 years. Accelerometry was used to measure time spent in light-intensity PA (LPA), moderate to vigorous PA (MVPA), and vigorous PA, and SB.

Effects of physical exercise on Akkermansia muciniphila: a systematic review of human and animal studies.

This systematic review aimed to compile various research designs, including experimental, longitudinal, cross-sectional, and case studies in humans and experimental studies in rodents, to examine changes in Akkermansia muciniphila abundance in response to exercise. This comprehensive approach can improve our understanding of A. muciniphila response to physical exercise and highlight gaps in the literature, providing valuable insights for future microbiome research.

Efficacy, safety of and adherence to adjustable compression wraps in the control phase of breast cancer-related lymphedema: A randomized controlled trial.

Objective: To evaluate efficacy, safety, and adherence to using adjustable compression wraps (ACWs) for upper limb volume control in women with breast cancer-related lymphedema.

Design And Setting: Randomized controlled trial at a reference hospital for breast cancer treatment in Brazil.

Participants: Women in control phase of the breast cancer-related lymphedema.

Malignant melanoma in Portuguese adult population: a scoping review of the real-world evidence.

Purpose: Malignant melanoma is an aggressive cancer, and there is a notable dearth on epidemiology, clinical and treatment characterization within the Portuguese population. We performed a scoping review to identify real-world evidence studies focused in Portuguese adult patients with malignant melanoma.

Methods: A comprehensive search was conducted.

CLINICAL AND EPIDEMIOLOGIC EVALUATION OF DESMOID TUMORS IN A BRAZILIAN SARCOMA REFERENCE CENTER.

Introduction: Desmoid Tumors (DT) are rare neoplasms with higher incidence in younger women.

Methods: Retrospective, single-center analysis of patients with DT. Variables were age, sex, biopsy, treatment and recurrence.

Factors delaying non-metastatic breast cancer adjuvant therapy and impact on prognosis in a cohort of Brazilian women.

Objective: To identify factors associated with delays in beginning adjuvant therapy and prognosis impacts on non-metastatic breast cancer patients.

Methods: This assessment comprised a prospective cohort study concerning breast cancer patients treated at a public oncology centre. A time interval of ≥60 days between surgery and the beginning of the first adjuvant treatment was categorised as a delay.

Compressive taping to prevent postmastectomy seroma: patient adherence and satisfaction.

Objective: Evaluate patient adherence and satisfaction concerning postmastectomy compressive taping.

Methods: This comprises a preintervention and postintervention study carried out with women ≥18 years old who underwent taping during the first 7 postoperative days at the Cancer Hospital III/National Cancer Institute. Good adherence was considered as taping maintenance for 7 days.

Role of magnetic resonance imaging in the prediction of histological grade in soft tissue sarcomas.

Background: Soft tissue sarcomas are rare malignant tumors with significant heterogeneity. The importance of classifying histological grades is fundamental to defining the treatment approach.

Objective: To evaluate magnetic resonance imaging (MRI) in predicting the histological grade of soft tissue sarcomas.

Liposomal Rifabutin-A Promising Antibiotic Repurposing Strategy against Methicillin-Resistant Infections.

Methicillin-resistant (M RSA) infections, in particular biofilm-organized bacteria, remain a clinical challenge and a serious health problem. Rifabutin (RFB), an antibiotic of the rifamycins class, has shown in previous work excellent anti-staphylococcal activity. Here, we proposed to load RFB in liposomes aiming to promote the accumulation of RFB at infected sites and consequently enhance the therapeutic potency.

Phenotypic Characterization of Patients with Polycystic Ovary Syndrome in a Population from the Ecuadorian Andes: A Cross-Sectional Study.

Polycystic ovary syndrome (PCOS) is a highly prevalent endocrine-metabolic disorder in women of reproductive age. Diagnosis is based on the evidence-based international guideline 2018 and the Rotterdam Consensus to classify PCOS phenotypes. This study aims to characterize the biodemographic, clinical, metabolic, and reproductive variables and their relationship with PCOS phenotypes in a population from the Ecuadorian Andes.

Climate change and land cover effects on water yield in a subtropical watershed spanning the yungas-chaco transition of Argentina.

The demand for mountain water resources is increasing, and their availability is threatened by climate change, emphasizing the urgency for effective protection and management. The upper Sali-Dulce watershed holds vital significance as it contributes the majority of the Sali-Dulce water resources, supporting a densely populated dry region in Northwestern Argentina, covering an area of 24,217 km. However, the potential impact of climate change and land use/land cover change on water yield in this watershed remains uncertain.

Intracranial non-germinomatous germ cell tumors in children and adolescents: how can the experience from an uppermiddle-income country contribute to the worldwide effort to improve outcomes?

Background: Non-germinomatous germ cell tumors (NGGCT) accounts for one third of intracranial GCT. While the germinoma group have an excellent overall survival, the standard of practice for children with NGGCT is still under evaluation.

Aims: Describe the results of the of the Brazilian consortium protocol.

Probable sleep and awake bruxism in adolescents: A path analysis.

Background: Bruxism has a multifactorial etiology, including the influence of sleep characteristics and chronotypes.

Aim: To identify the pathways that influence the occurrence of probable sleep bruxism (PSB) and probable awake bruxism (PAB) in adolescents.

Design: A total of 403 adolescents, aged 12-19 years, participated in the study.

Moving from ecological impacts to social vulnerability in data-scarce places.

Managers need to trace social impacts and vulnerability caused by environmental change all the way to its driving forces to target key system components for intervention. However, most available scientific evidence deals with either the ecological impacts of direct drivers or the value of ecosystem benefits to people. Our matrix-based tool combines these types of evidence to make environmental management problems traceable through a structured yet flexible procedure.

Effects of resistance training associated with a verbal fluency task on physical performance and cognitive function in frail nursing home residents.

Objectives: Studies examining the effects of dual-task resistance training (RT) on nursing-home residents are still scarce. To add knowledge to this field, the present study compared the effects of 12-week RT and RT plus cognitive task (COG) programs on physical performance and cognitive function in a sample of frail nursing home residents.

Methods: This is an experimental study that combined data from two studies that examined older adults living in nursing home residences in Brazil.

Age- and sex-specific normative values for muscle mass parameters in 18,625 Brazilian adults.

Background: The present study aimed to provide age- and sex-specific normative values for muscle mass parameters in Brazilian adults.

Methods: Data pertaining to Brazilian adults (18+ years) who attended a nutritional clinical between January 2018 and July 2022 were analyzed. Muscle mass parameters were assessed using a bioimpedance digital scale (InBody 230, GBC BioMed NZ).