Publications by authors named "Agostino Brizzi"
The etiology of the pregnancy syndrome preeclampsia is still unclear, while most hypotheses center on the placenta as the major contributor of the syndrome. Especially changes of the placental metabolism, including the use of glucose to produce energy, are important features. As an example, inositol phosphoglycan P-type molecules, second messengers involved in the glucose metabolism of all cells, can be retrieved from maternal urine of preeclamptic women, even before the onset of clinical symptoms.
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- The text discusses transfusion management during post-partum hemorrhage (PPH), which is a major cause of maternal death, and highlights the usefulness of standard and point-of-care tests in guiding treatment.
- It reveals critical issues in the management of PPH, such as poor communication among healthcare professionals, delays in diagnosis, and inadequate monitoring, based on data from the Italian Obstetric Surveillance System.
- The authors advocate for a targeted approach to transfusion therapy using advanced coagulation monitoring techniques (ROTEM and TEG) and stress the importance of a multidisciplinary approach and standardized protocols to improve clinical practices.