Publications by authors named "Agostina Ronca"

Article Synopsis
  • * A study developed a CRISPR/Cas9 genome editing technique to create resistant 'Italiko' basil plants by mutating the DMR6 gene, achieving a high rate of successful genetic transformation.
  • * The resulting T0 plants exhibited various mutations, inherited in T1 seedlings, with one line (22B) showing minimal disease incidence and a preserved aromatic profile rich in oxygenated monoterpenes.
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Fungal prosthetic joint infection (PJI) is a rare but severe complication of artroplasty. We report a case of PJI due to azole-resistant Candida albicans successfully treated with combination of prolonged administration of anidulafungin and two-stage joint exchange with insertion of a mega-prosthesis.

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The differential diagnosis between asepting loosening or prosthetic joint infection is not always easy. Tc-99m-labelled leucocyte scans, frozen section and histology can help recognise doubtful cases. We report the experience of the Unit for Infectious Diseases and Septic Orthopaedics of the ASL-2 Liguria, Italy, with a Tc-99m-labelled leucocyte scan and intraoperative frozen section to choose the best therapeutic approach: one-stage or two-stage exchange or arthrodesis-arthroplastica.

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Introduction: Tubercular infection of prosthetic joint arthroplasty is sporadically described, but its incidence is rising. Misdiagnosis is common because of disparate clinical presentation.

Presentation Of Case: We describe 1 hand, 2 hip and 2 knee prosthetic-joint infections due to Mycobacterium tuberculosis in patients without a previous history of tuberculosis.

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