[Nifedipine and kidney tubular function].

Aim of the study was to evaluate the influence of nifedipine on the proximal tubular handling of sodium, as judged by variations in the fractional excretion of lithium, which is a simple and reliable indicator of sodium and water reabsorption at this site. Lithium clearance was determined in 17 in-hospital essential hypertensives who took 16 mmol of lithium per os at 10 p.m.