Comparison of a Novel Ultra-Widefield Three-Color Scanning Laser Ophthalmoscope to Other Retinal Imaging Modalities in Chorioretinal Lesion Imaging.

Purpose: To compare the assessment of clinically relevant retinal and choroidal lesions as well as optic nerve pathologies using a novel three-wavelength ultra-widefield (UWF) scanning laser ophthalmoscope with established retinal imaging techniques for ophthalmoscopic imaging.

Methods: Eighty eyes with a variety of retinal and choroidal lesions were assessed on the same time point using Topcon color fundus photography (CFP) montage, Optos red/green (RG), Heidelberg SPECTRALIS MultiColor 55-color montage (MCI), and novel Optos red/green/blue (RGB). Paired images of the optic nerve, retinal, or choroidal lesions were initially diagnosed based on CFP imaging.

Constraints for Rare Electron-Capture Decays Mimicking Detection of Dark-Matter Particles in Nuclear Transitions.

We give for the first time theoretical estimates of unknown rare electron-capture (EC) decay branchings of ^{44}Ti, ^{57}Co, and ^{139}Ce, relevant for searches of (exotic) dark-matter particles. The nuclear-structure calculations have been done exploiting the nuclear shell model with well-established Hamiltonians and an advanced theory of β decay. In the absence of experimental measurements of these rare branches, these estimates are of utmost importance for terrestrial searches of dark-matter particles, such as axionic dark matter in the form of axionlike particles, anapole dark matter, and dark photons in nuclear transitions.

Cross-instrument optical coherence tomography-angiography (OCTA)-based prediction of age-related macular degeneration (AMD) disease activity using artificial intelligence.

This study investigates the efficacy of predicting age-related macular degeneration (AMD) activity through deep neural networks (DNN) using a cross-instrument training dataset composed of Optical coherence tomography-angiography (OCTA) images from two different manufacturers. A retrospective cross-sectional study analyzed 2D vascular en-face OCTA images from Heidelberg Spectralis (1478 samples: 1102 training, 276 validation, 100 testing) and Optovue Solix (1003 samples: 754 training, 189 validation, 60 testing). OCTA scans were labeled based on clinical diagnoses and adjacent B-scan OCT fluid information, categorizing activity into normal, dry AMD, active wet AMD, and wet AMD in remission.

Isolation and molecular characterization of fowl adenovirus from inclusion body hepatitis cases in Western India during 2019-2021.

Background: Inclusion body hepatitis (IBH) resulted in a substantial economic loss in Western India during 2019 to 2021.

Aims: The study aimed to characterize fowl adenovirus (FAdV) from field outbreaks.

Methods: The study was conducted on 290 liver samples from 66 poultry flocks.

Prevalence, Attributes, and Risk Factors of QT-Interval-Prolonging Drugs and Potential Drug-Drug Interactions in Cancer Patients: A Prospective Study in a Tertiary Care Hospital.

Introduction Cancer chemotherapy regimens include multiple classes of adjuvant drugs as supportive therapy. Because of the concurrent intake of other drugs (like antiemetics, antidepressants, analgesics, and antimicrobials), there is a heightened risk for possible QT interval prolongation. There is a dearth of evidence in the literature regarding the usage of QT-prolonging anticancer drugs and associated risk factors that have the propensity to prolong QT interval.

Genetic manipulation of Indian mustard genotypes with WRR-gene(s) confers resistance against Albugo candida.

Background: Brassica species is the second most important edible oilseed crop in India. Albugo candida (Pers.) Kuntze, a major oomycete disease of oilseed brassica causing white rust, leads to 60% yield loss globally.

Clip Dislodgement After Full-Thickness Endoscopic Resection Device Removal of Scarred Gastric Subepithelial Lesion Leading to Delayed Perforation.

Endoscopic full-thickness resection using a full-thickness resection device is a newer technique for endoscopic removal of submucosal lesions not amenable to endoscopic mucosal resection or endoscopic submucosal dissection. There is a low rate of complications reported, although we report 2 cases of delayed perforation caused by dislodgement of a full-thickness resection device clip after removal of scarred gastric lesions. Both were managed endoscopically with good outcomes.

Variations in adult BMI among Indian men: a quantile regression analysis.

India has not only maintained its top position among countries with the largest number of underweight adults but has also jumped to a higher position among countries with largest increase in the proportion of overweight people in the last three decades. More studies focus on double burden of malnutrition among women than on men. This study uses the quantile regression model to analyse the covariates associated with low and high body mass index (BMI) primarily among men aged 20-54 years during 2015-2016 in India.

Randomized trial of gastric and colorectal endoscopic submucosal dissection defect closure comparing a novel through-the-scope suturing system with an over-the-scope suturing system (with video).

Background And Aims: Mucosal closure adds time but reduces adverse events associated with endoscopic submucosal dissection (ESD). We aimed to assess the closure time (CT), technical success, and cost-effectiveness between a novel through-the-scope helix tack suture system (TTSS) and the over-the-scope suturing system (OTSS).

Methods: In this single-center, prospective, randomized trial, all patients undergoing ESD with anticipated closure were randomized 1:1 to TTSS (study group) or OTSS (control group).

Tobacco Turmoil in Teens and Preparedness of Pediatric Dentists: A Global Survey.

Background: Tobacco use amongst adolescents causes significant health problems affecting almost all organs and has a significant effect on normal growth and development. Smoker adolescents are also more prone to oral health problems than nonsmokers. Pediatric dentists can play a significant role in providing tobacco cessation counseling to adolescents.

Melanoma-the therapeutic considerations in the clinical practice.

The incidence of melanoma is increasing and prolonged exposure to ultraviolet (UV) radiation remains the main risk factor. Public health measures have been vital in tackling the increased incidence and prevalence of melanoma. The management of melanoma has been revolutionised with the approval of new immunotherapy treatments (anti PD-1, CTLA-4 and LAG-3 antibodies) and targeted therapies (BRAF and MEK inhibitors).

Making Meaning Together: Co-designing a Social Robot for Older Adults with Ikigai Experts.

A sense of meaning and purpose in life-known in Japan as one's ikigai-can lead to better health outcomes, an improved sense of well-being, and longer life as people age. The design of socially assistive robots, however, has so far focused largely on the more hedonic aims of supporting positive affect and happiness through interactions with robots. To explore how social robots might be able to support people's ikigai, we performed (1) in-depth interviews with 12 'ikigai experts' who formally support and/or study older adults (OAs)' ikigai and (2) 5 co-design workshop sessions with 10 such experts.

Salvage endoscopic ultrasound-guided gastrojejunostomy as a bridge to definitive surgical therapy for duodenal adenocarcinoma presenting with duodenal stent obstruction.

The utilization of endoscopic ultrasound-guided gastrojejunostomy (EUS-GJ) in the setting of an obstructed (ingrown) duodenal stent as a bridge to pancreaticoduodenectomy (PD) remains undescribed. Herein, we report a case study of a 51-year-old patient who underwent EUS-GJ using lumen apposing metal stent (LAMS) for an obstructed duodenal stent during neoadjuvant treatment for duodenal adenocarcinoma. The patient ultimately underwent surgical resection by a classic PD 14 weeks after LAMS placement.

Double Whammy Due to Coronavirus Disease-2019: Invasive Small Bowel Mucormycosis with Recent-Onset Diabetic Ketoacidosis Presenting as Diffuse Fecal Peritonitis in a 12-Year-Old Girl.

Mucormycosis is a fatal fungal infection occurring in immunocompromised patients. Small bowel mucormycosis is extremely rare with a high mortality rate. We report the case of a 12-year-old girl with postcoronavirus disease (COVID) recent-onset diabetic ketoacidosis, who presented with acute abdomen with fecal peritonitis.

Prediction of Flood Discharge Using Hybrid PSO-SVM Algorithm in Barak River Basin.

A crucial necessity in integrated water resource management is flood forecasting. Climate forecasts, specifically flood prediction, comprise multifaceted tasks as they are dependant on several parameters for predicting the dependant variable, which varies from time to time. Calculation of these parameters also changes with geographical location.

Isolation and molecular characterization of infectious bursal disease virus circulating in western and central India.

Background: Infectious bursal disease (IBD) caused substantial economic loss in central and western India during 2020 and 2021.

Aims: The study was conducted to characterize IBD virus (IBDV) from field outbreaks.

Methods: The study was conducted on 360 samples from 42 poultry flocks.

Can Below-Knee Casts be Effective for Clubfoot Management in Walking-Age Children? A Prospective Cohort Study.

Purpose: Above-knee casts pose a major challenge in the day-to-day activities among walking age clubfoot patients due to complete restriction of knee movement. This current study investigates the effectiveness of below-knee casts compared to above-knee casts for managing walking age clubfoot deformity.

Methods: After approval from the institutional ethical committee, we enrolled walking age clubfoot patients for deformity correction through corrective manipulation and casting through below-knee casts over 2 years.

Finding : How robots can support meaning in later life.

Previous research in human-robot interaction has explored using robots to increase objective and hedonic aspects of well-being and quality of life, but there is no literature on how robots might be used to support eudaimonic aspects of well-being (such as meaning in life). A sense of meaning has been shown to positively affect health and longevity. We frame our study around the Japanese concept of , which is widely used with Japanese older adults to enhance their everyday lives, and is closely related to the concept of eudaimonic well-being (EWB) known in Western countries.

Analysing the relationship between human modification and land surface temperature fluctuation in the Ramganga basin, India.

In many regions across the world, including river basins, population growth and land development have enhanced the demand for land and other natural resources. The anthropogenic activities can be detrimental to the vital ecosystems that sustain the river basin region. This work assessed the impact of human modification on land surface temperature (LST) for the Ramganga basin in India.

Molecular phylodynamics of fowl adenovirus serotype 11 and 8b from inclusion body hepatitis outbreaks.

Fowl adenovirus (FAdV) serotypes are involved in a variety of clinical manifestations in poultry and has resulted in substantial economic loss to the poultry farmers. Despite the endemicity of Inclusion body hepatitis (IBH) in South Asian countries, including India, its etiology is not well studied. In western India, the rural poultry flocks obtained from the vaccinated parents were experiencing disease outbreaks with substantial economic losses due to heavy outbreaks and mortality.

Time series forecasting of temperature and turbidity due to global warming in river Ganga at and around Varanasi, India.

The fluctuation in the river ecosystem network due to climate change-induced global warming affects aquatic organisms, water quality, and other ecological processes. Assessment of climate change-induced global warming impacts on regional hydrological processes is vital for effective water resource management and planning. The global warming effect on river water quality has been analyzed in this work.

Analysis of algal bloom intensification in mid-Ganga river, India, using satellite data and neural network techniques.

River Ganga is one of the most significant rivers in the country. This river is the adobe for numerous aquatic species and microorganisms. The color of the river suddenly changed to green due to the rise of algal bloom in the Varanasi and nearby regions of the river Ganga during May-June 2021.