Sediment load assessments under climate change scenarios and a lack of integration between climatologists and environmental modelers.

Increasing precipitation accelerates soil erosion and boosts sediment loads, especially in mountain catchments. Therefore, there is significant pressure to deliver plausible assessments of these phenomena on a local scale under future climate change scenarios. Such assessments are primarily drawn from a combination of climate change projections and environmental model simulations, usually performed by climatologists and environmental modelers independently.

Machine Learning Analyzed Weather Conditions as an Effective Means in the Predicting of Acute Coronary Syndrome Prevalence.

Background: The prediction of the number of acute coronary syndromes (ACSs) based on the weather conditions in the individual climate zones is not effective. We sought to investigate whether an artificial intelligence system might be useful in this prediction.

Methods: Between 2008 and 2018, a total of 105,934 patients with ACS were hospitalized in Lesser Poland Province, one covered by two meteorological stations.

Variability of growing degree days in Poland in response to ongoing climate changes in Europe.

An observed increase in air temperature can lead to significant changes in the phenology of plants and, consequently, changes in agricultural production. The aim of the study was to evaluate the spatial differentiation of thermal resources in Poland and their variability during a period of changing thermal conditions in Europe. Since the variability of thermal conditions is of paramount importance for perennial crops, the study focused on apple, plum, and cherry orchard regions in Poland.

Promoter methylation and expression levels of selected hematopoietic genes in pediatric B-cell acute lymphoblastic leukemia.

Background: Precursor B-cell acute lymphoblastic leukemia (B-cell ALL) is the most common neoplasm in children and is characterized by genetic and epigenetic aberrations in hematopoietic transcription factor (TF) genes. This study evaluated promoter DNA methylation and aberrant expression levels of early- and late-acting hematopoietic TF genes homeobox A4 and A5 (HOXA4 and HOXA5), Meis homeobox 1 (MEIS1), T-cell acute lymphocytic leukemia 1 (TAL1), and interferon regulatory factors 4 and 8 (IRF4 and IRF8) in pediatric B-cell ALL.

Methods: Blood samples of 38 ALL patients and 20 controls were obtained.

TET2 Promoter DNA Methylation and Expression Analysis in Pediatric B-cell Acute Lymphoblastic Leukemia.

TET2 is a novel tumor suppressor gene involved in several hematological malignancies of myeloid and lymphoid origin. Besides loss-of-function mutations and deletions, hypermethylation of the CpG island at the TET2 promoter was found in human cancer. Previous analysis revealed no TET2 mutations in acute lymphoblastic leukemia (ALL).

[5- year old boy with Weber-Christian Syndrome or histiocytic cytophagic panniculitis? Diagnostic difficulties. Case presentation].

The aim of the paper is to present a case of a 5-year-old boy hospitalised because of recurrent high temperature and reddish blue infiltration of skin and hypodermis lasting 3 months. Because of pancytopenia and hepatomegaly, we suspected a proliferative disease of the haematopoietic or lymphatic system. Several bone marrow biopsies, did not show neoplastic changes.

[Evaluation of systolic and diastolic function of the left ventricle in children with acute lymphoblastic leukaemia before treatment].

Between 1995 and 2001 echo-cardiography was performed in 244 children (128 boys, 116 girls) with acute lymphoblastic leukaemia (ALL) before the beginning of therapy with anthracyclines (medium 5.4 days after the diagnosis). The mean age at diagnosis was 5.

[Preliminary results of the use of MRD test among children with acute lymphoblastic leukaemia].

Unlabelled: The purpose of the study was to monitor minimal residue disease (MRD) among children with ALL and to evaluate the possibility of using this test to detect and monitor the minimal residual disease (MRD test) in the stratification of risk groups on a parallel basis with other recognised prognostic factors.

Materials And Methods: 56 children, with de novo diagnosed ALL, comprised test group. Control group consisted of 10 healthy persons.