Evaluation of electrocardiographic parameters in patients with hearing loss genotyped for the connexin 26 gene (GJB2) mutations.

Introduction: Several studies have associated congenital sensorineural hearing loss in children with prolongation of the cardiac parameter QTc. The cause of this association is unknown. At the same time, mutations in GJB2, which encodes connexin 26, are the most common cause of congenital hearing impairment.

QTc prolongation in patients with hearing loss: Electrocardiographic and genetic study.

Background: The aim of the study was to determine, whether electrocardiogram (ECG) screening could reduce the risk of sudden cardiac death in patients with hearing loss through the early diagnosis of Jervell and Lange-Nielsen syndrome and the introduction of the therapy.

Methods: One thousand and eighty patients with hearing loss (aged 21.8 ± 19.

[Second-degree atrioventricular block in a patient with coexistant intermittent preexcitation syndrome that masks the electrocardiographic features of past myocardial infarction - diagnostic difficulties and management].

We describe a case of a 60 year-old man after inferior wall myocardial infarction with intermittent preexcitation syndrome. In ECG, the pathologic Q waves in the inferior leads were masked by the intermittent preexcitation. In this patient, paroxysmal asymptomatic second-degree atrioventicular block coexists with inconstant atrioventricular conduction maintained by the accessory pathway, periodically 2:1.