Publications by authors named "Agnieszka Machlanska"
Background: Hemophagocytic lymphohistiocytosis (HLH) is a rarely recognized hyperinflammatory condition of high death risk.
Objective: The objective was to describe a case of HLH in a patient with multiple sclerosis (MS) treated with ocrelizumab.
Methods: Clinical observation, laboratory testing, and use of HLH-2004 criteria for HLH diagnosis.
Article Synopsis
- * This study found that specific miRNAs (miR-301a, miR-21, and miR-155) were significantly upregulated in CD4(+) T cells upon stimulation with myelin autoantigen, MOG(35-55), and were overexpressed in T cells in the central nervous system of animals with autoimmune encephalomyelitis.
- * miR-301a was shown to promote T-helper type 17 cell development by targeting the IL-6/23-STAT3 pathway, and manipulating miR-301