Publications by authors named "Agnese Sbrollini"

Electroencephalography (EEG) wearable devices are particularly suitable for monitoring a subject's engagement while performing daily cognitive tasks. EEG information provided by wearable devices varies with the location of the electrodes, the suitable location of which can be obtained using standard multi-channel EEG recorders. Cognitive engagement can be assessed during working memory (WM) tasks, testing the mental ability to process information over a short period of time.

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Timely and reliable fetal monitoring is crucial to prevent adverse events during pregnancy and delivery. Fetal phonocardiography, i.e.

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The database is constituted by 50 datasets containing cardiorespiratory signals acquired from 50 healthy volunteer subjects (one dataset for each subject; 23 males and 27 females; age: 23±5 years) while performing normal breathing, deep breathing, and breath holding, and two spreadsheet files, namely the "SubjectsInfo.xlsx" and "DBInfo.xlsx" containing the metadata of subjects (including demographic data) and of acquired signals, respectively.

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Goal: To evaluate suitability of respiratory signals derived from clinical 12-lead electrocardiograms (ECGs) and wearable 1-lead ECG to identify different respiration types.

Methods: ECGs were simultaneously acquired through the M12R ECG Holter by Global Instrumentation and the chest strap BioHarness 3.0 by Zephyr from 42 healthy subjects alternating normal breathing, breath holding, and deep breathing.

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Sudden cardiac death is the leading cause of death among cardiovascular diseases. Markers for patient risk stratification focusing on QT-interval dynamics in response to heart-rate (HR) changes can be characterized in terms of parametric QT to RR dependence and QT/RR hysteresis. The QT/RR hysteresis can be quantified by the time delay the QT interval takes to accommodate for the HR changes.

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Non-Small Cell Lung Cancer (NSCLC) accounts for about 85% of all lung cancers. Developing non-invasive techniques for NSCLC histology characterization may not only help clinicians to make targeted therapeutic treatments but also prevent subjects from undergoing lung biopsy, which is challenging and could lead to clinical implications. The motivation behind the study presented here is to develop an advanced on-cloud decision-support system, named LUCY, for non-small cell LUng Cancer histologY characterization directly from thorax Computed Tomography (CT) scans.

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This review systematically examined the scientific literature about electroencephalogram-derived ratio indexes used to assess human mental involvement, in order to deduce what they are, how they are defined and used, and what their best fields of application are. (2) Methods: The review was carried out according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. (3) Results: From the search query, 82 documents resulted.

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. Acute myocardial ischemia in the setting of acute coronary syndrome (ACS) may lead to myocardial infarction. Therefore, timely decisions, already in the pre-hospital phase, are crucial to preserving cardiac function as much as possible.

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Knowledge about the anatomical structures of the left heart, specifically the atrium (LA) and ventricle (i.e., endocardium-Vendo-and epicardium-LVepi) is essential for the evaluation of cardiac functionality.

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American football is the sport with the highest rates of concussion injuries. Biomedical engineering applications may support athletes in monitoring their injuries, evaluating the effectiveness of their equipment, and leading industrial research in this sport. This literature review aims to report on the applications of biomedical engineering research in American football, highlighting the main trends and gaps.

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Wearable and portable devices capable of acquiring cardiac signals are at the frontier of the sport industry. They are becoming increasingly popular for monitoring physiological parameters while practicing sport, given the advances in miniaturized technologies, powerful data, and signal processing applications. Data and signals acquired by these devices are increasingly used to monitor athletes' performances and thus to define risk indices for sport-related cardiac diseases, such as sudden cardiac death.

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Background And Objective: Alzheimer's disease accounts for approximately 70% of all dementia cases. Cortical and hippocampal atrophy caused by Alzheimer's disease can be appreciated easily from a T1-weighted structural magnetic resonance scan. Since a timely therapeutic intervention during the initial stages of the syndrome has a positive impact on both disease progression and quality of life of affected subjects, Alzheimer's disease diagnosis is crucial.

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Aims: The standard deviation of activation time (SDAT) derived from body surface maps (BSMs) has been proposed as an optimal measure of electrical dyssynchrony in patients with cardiac resynchronization therapy (CRT). The goal of this study was two-fold: (i) to compare the values of SDAT in individual CRT patients with reconstructed myocardial metrics of depolarization heterogeneity using an inverse solution algorithm and (ii) to compare SDAT calculated from 96-lead BSM with a clinically easily applicable 12-lead electrocardiogram (ECG).

Methods And Results: Cardiac resynchronization therapy patients with sinus rhythm and left bundle branch block at baseline (n = 19, 58% males, age 60 ± 11 years, New York Heart Association Classes II and III, QRS 167 ± 16) were studied using a 96-lead BSM.

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Atrial fibrillation (AF) is a common supraventricular arrhythmia. Its automatic identification by standard 12-lead electrocardiography (ECG) is still challenging. Recently, deep learning provided new instruments able to mimic the diagnostic ability of clinicians but only in case of binary classification (AF vs.

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Non-Small Cell Lung Cancer (NSCLC) represents up to 85% of all malignant lung nodules. Adenocarcinoma and squamous cell carcinoma account for 90% of all NSCLC histotypes. The standard diagnostic procedure for NSCLC histotype characterization implies cooperation of 3D Computed Tomography (CT), especially in the form of low-dose CT, and lung biopsy.

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This review analyzes scientific data published in the first two years of the COVID-19 pandemic with the aim to report the cardiorespiratory complications observed after SARS-CoV-2 infection in young adult healthy athletes. Fifteen studies were selected using PRISMA guidelines. A total of 4725 athletes (3438 males and 1287 females) practicing 19 sports categories were included in the study.

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Myocardial ischemia, consisting in a reduction of blood flow to the heart, may cause sudden cardiac death by myocardial infarction or trigger serious abnormal rhythms. Thus, its timely identification is crucial. The Repeated Structuring and Learning Procedure (RS&LP), an innovative constructive algorithm able to dynamically create neural networks (NN) alternating structuring and learning phases, was previously found potentially useful for myocardial ischemia detection.

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Introduction: Drug-induced block of the hERG potassium channel could predispose to torsade de pointes, depending on occurrence of concomitant blocks of the calcium and/or sodium channels. Since the hERG potassium channel block affects cardiac repolarization, the aim of this study was to propose a new reliable index for non-invasive assessment of drug-induced hERG potassium channel block based on electrocardiographic T-wave features.

Methods: ERD (early repolarization duration) and T (down-going T-wave slope to T-wave amplitude ratio) features were measured in 22 healthy subjects who received, in different days, doses of dofetilide, ranolazine, verapamil and quinidine (all being hERG potassium channel blockers and the latter three being also blockers of calcium and/or sodium channels) while undergoing continuous electrocardiographic acquisition from which ERD and T were evaluated in fifteen time points during the 24 h following drug administration ("ECG Effects of Ranolazine, Dofetilide, Verapamil, and Quinidine in Healthy Subjects" database by Physionet).

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Acute Ischemic Stroke (AIS) is defined as the acute condition of occlusion of a cerebral artery and is often caused by a Hypertensive Condition (HC). Due to its sudden occurrence, AIS is not observable the right moment it occurs, thus information about instantaneous changes in hemodynamics is limited. This study aimed to propose an integrated Lumped Parameter (LP) model of the cardiovascular system to simulate an AIS and describe instantaneous changes in hemodynamics.

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Background: Stroke is a leading cause of disability, injury, and death in elderly people and represents a major public health problem with substantial medical and economic consequences. The incidence of stroke rapidly increases with age, doubling for each decade after age 55 years. Gait impairment is one of the most important problems after stroke, and improving walking function is often a key component of any rehabilitation program.

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Atrial fibrillation (AF) is a common cardiac disorder that can cause severe complications. AF diagnosis is typically based on the electrocardiogram (ECG) evaluation in hospitals or in clinical facilities. The aim of the present work is to propose a new artificial neural network for reliable AF identification in ECGs acquired through portable devices.

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The proposed dataset provides annotations for the 552 cardiotocographic (CTG) recordings included in the publicly available "CTU-CHB intra-partum CTG database" from Physionet (https://physionet.org/content/ctu-uhb-ctgdb/1.0.

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The database here described contains data of integrated surveillance for the "Coronavirus disease 2019" (abbreviated as COVID-19 by the World Health Organization) in Italy, caused by the novel coronavirus SARS-CoV-2. The database, included in a main folder called COVID-19, has been designed and created by the Italian Civil Protection Department, which currently manages it. The database consists of six folders called 'aree' (containing charts of geographical areas interested by containment measures), 'dati-andamento-nazionale' (containing data relating to the national trend of SARS-CoV-2 spread), 'dati-json' (containing data that summarize the national, provincial and regional trends of SARS-CoV-2 spread), 'dati-province' (containing data relating to the provincial trend of SARS-CoV-2 spread), 'dati-regioni' (containing data relating to the regional trend of SARS-CoV-2 spread) and 'schede-riepilogative' (containing summary sheets relating to the provincial and regional trends of SARS-CoV-2 spread).

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The database is a collection of postural data acquired from 10 patients affected by the rare Stargardt's syndrome, all having the ABCA4 gene mutation, and from 10 control healthy subjects. Specifically, the database includes a file (.xlxs) called SubjectsData and 20 datasets (MATLAB structures) containing postural signals.

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Background: Sudden infant death syndrome is more frequent in preterm infants (PTI) than term infants and may be due to cardiac repolarization instability, which may manifest as T-wave alternans (TWA) on the electrocardiogram (ECG). Therefore, the aim of the present work was to analyze TWA in nonpathological PTI and to open an issue on its physiological interpretation.

Methods: Clinical population consisted of ten nonpathological PTI (gestational age ranging from 29 to 34  weeks; birth weight ranging from 0.

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