Publications by authors named "Agnes Lasheras"
Background: Extended-spectrum beta-lactamases-producing (ESBL-E) are disseminating worldwide especially in Intensive Care Units (ICUs) and are responsible for increased health costs and mortality. The aims of this work were to study ESBL-E dissemination in ICU and to assess the impact of ESBL-E fecal carriage on subsequent infections during a non-outbreak situation.
Methods: We therefore screened every patient at admission then once a week in a medical ICU between January and June 2015.
Article Synopsis
- Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) are spreading globally, particularly in ICUs, leading to longer hospital stays and higher mortality rates.
- The initial response to outbreaks involved systematic fecal carriage screening and hygiene improvements, but there’s growing debate about its effectiveness as ESBL-E has also spread into the community.
- A systematic review of existing studies suggests that routine screening may not significantly reduce ESBL-E transmission or infections, and discontinuing such screening could potentially lower carbapenem use in ICUs.
Background: This study was undertaken to determine the temporal relationship between implementation of different interventions in an intensive care unit (ICU) and control of endemic nosocomial acquisition of extended-spectrum β-lactamase Enterobacteriaceae (ESBLE).
Methods: This was a prospective observational study with time-series analysis of the monthly incidence of ESBLE and its predictors. In November 2007, after a 14-month baseline period, an intervention consisting of restriction of third-generation cephalosporins (3 GC) and increased use of alcohol-based hand rubs was implemented.
The reservoir for hospital-acquired Legionnaires' disease has been shown to be the potable water distribution system. The objectives of the present study were as follows: (1) to examine the possible relationship between physical-chemical characteristics of water such as temperature, pH, hardness, conductivity, and residual chlorine and the presence of amoebae as growth-promoting factors for Legionella species and (2) to determine eradication measures for water distribution systems to seek ways of reducing the risk of legionellosis. Ten hospitals in southwest France took part in this study.
View Article and Find Full Text PDFBackground: Use of protective devices has become a common intervention to decrease sharps injuries in the hospitals; however few studies have examined the results of implementation of the different protective devices available.
Objective: To determine the effectiveness of 2 protective devices in preventing needlestick injuries to health care workers.
Methods: Sharps injury data were collected over a 7-year period (1993-1999) in a 3600-bed tertiary care university hospital in France.