Involvement of Executive Functions in Idiom Comprehension: A Life-Span Perspective.

Objectives-Our aim is to investigate the executive functions involved in idiom comprehension. The understanding of idioms has largely been explored from a developmental perspective. However, little is known about the cognitive processes involved.

Neuroticism, perfectionism, and emotion suppression in burnout: Implications for cognitive functioning.

This study aimed to investigate the relationship between burnout and cognitive functions, particularly memory, attention, and executive functions, which have been found to be negatively affected in most studies. However, the results are not consistent across studies, and there is often a discrepancy between self-reported cognitive function and objective assessment. Two possible explanations for this discrepancy are the heterogeneous profiles of individuals in burnout and their personality traits.

The French Version of the DABS: Adaptation Process and Preliminary Field Test.

The aim of this study was to develop a transcultural adaptation of the Diagnostic Adaptive Behavior Scale (DABS) in French and to perform a field evaluation of the adapted version of the tool (DABS-F). Eight experts in intellectual and developmental disabilities (IDD) and two professional translators formed two committees to translate the instrument. Thirty-four independent experts in IDD rated the clarity and relevance of the DABS-F.

Executive functioning in adolescents and adults with Silver-Russell syndrome.

Silver-Russell syndrome (SRS) is a rare imprinting disorder characterized by prenatal and postnatal growth retardation. The two principal causes of SRS are loss of methylation on chromosome 11p15 (11p15 LOM) and maternal uniparental disomy of chromosome 7 (UPD(7)mat). Knowledge of the neuropsychological profile of SRS remains sparse and incomplete even if several difficulties related to attention and learning have been reported both in the literature and by patients with SRS.

Quality of life and mental health of adolescents and adults with Silver-Russell syndrome.

Silver-Russell syndrome (SRS) is a rare imprinting disorder characterized by prenatal and postnatal growth retardation. Despite normal intellectual functioning, psychosocial and behavioral difficulties have been observed in this syndrome. However, few studies have dealt with these aspects, even though this could enhance the current understanding of the SRS and, more importantly, improve the management of potential psychosocial problems.

Factors Explaining Deficits in Reading Acquisition: The Case of Williams Syndrome.

Purpose Multiple factors impact reading acquisition in individuals with reading disability, including genetic disorders such as Williams syndrome (WS). Despite a relative strength in oral language, individuals with WS usually have an intellectual disability and tend to display deficits in areas associated with reading. There is substantial variability in their reading skills.

Maternal, foetal and child consequences of immunosuppressive drugs during pregnancy in women with organ transplant: a review.

Although pregnancy remains exceptional in women after heart, liver or lung transplant, obstetricians and nephrologists are regularly confronted with pregnancy in renal transplant recipients. National and international registries have described the epidemiology of maternal, foetal and neonatal complications, and transplantation societies have published recommendations on the monitoring of these high-risk pregnancies. In this review, we summarize the existing data on maternal and foetal complications of pregnancies in women after renal transplant, especially the management of immunosuppression.

[Pregnancies after kidney transplant: What are the consequences for the cognitive development of children?].

Thanks to medical progress in the field of kidney transplantation, the quality of life of women suffering from kidney failure has greatly improved in recent years. As a result, their fertility has increased significantly and pregnancies are now more frequent and safer. Kidney transplantation requires constant immunosuppressive treatment during pregnancy.

Prenatal exposure to glycol ethers and response inhibition in 6-year-old children: The PELAGIE cohort study.

Background: Exposure to glycol ethers (GEs) is suspected of impairing neurodevelopment in children, but the specific impact on their inhibitory capacity, a central deficit of ADHD, has never been studied. We aimed to assess the impact of prenatal exposure to GEs on the response inhibition of children aged six years.

Methods: In total, 169 mother-child pairs from the French cohort PELAGIE (2002-2006) were studied.

Intellectual functioning in Silver-Russell syndrome: First study in adults.

Silver-Russell syndrome (SRS) is a rare genetic disorder (estimated incidence 1/30,000 to 100,000 live births). So far, only a few studies have focused on the cognitive profile of individuals with SRS, and these were conducted some time ago, concentrated on pediatric cohorts, and included patients who had been diagnosed using a variety of clinical diagnostic systems. There has yet to be any research on the intellectual functioning of adults with SRS.

Acquisition of Reading and Intellectual Development Disorder.

We propose a review of the literature of the studies investigating reading acquisition in intellectual deficiency (ID), with particular focus on the explanatory factors for reading difficulties. Indeed, we explore the role of intellectual efficiency, perceptual abilities, oral language development, phonological processing and memory. The study of reading acquisition in ID is a challenge because of a high degree of heterogeneity in the results which, together with other variables influencing learning and development.

Prenatal Exposure to Glycol Ethers and Neurocognitive Abilities in 6-Year-Old Children: The PELAGIE Cohort Study.

Background: Glycol ethers (GE) are widely used organic solvents. Despite the potential neurotoxicity of several families of organic solvents, little is known about the impact of GE on the neurodevelopment of infants and children.

Objectives: We investigated the relation between urinary concentrations of GE metabolites in pregnant women and neurocognitive abilities in their 6-year-old children in the PELAGIE mother-child cohort.

Esquirol's change of view towards Pinel's mania without delusion.

We recount how Jean-Étienne Dominique Esquirol (1772-1840) gradually changed his position towards what Philipe Pinel (1745-1826) referred to as mania without delusion. Between 1805 and 1838, Esquirol moved from outright rejection, questioning the very idea of insane persons committing motiveless acts of violence without delusion, to relative acceptance. He eventually incorporated the clinical characteristics of mania without delusion in his description of homicidal monomania, dividing them between reasoning monomania and instinctive monomania.

Language and emotional abilities in children with Williams syndrome and children with autism spectrum disorder: similarities and differences.

Williams syndrome (WS) is a genetic disease with a relatively homogeneous profile: relatively well-preserved language, impaired cognitive activities, and hypersociability. Autism spectrum disorder (ASD) refers to a group of individuals with impairments in aspects of communication and a particular pattern of language acquisition. Although ASD and WS are polar opposites when it comes to communication abilities (language and emotion) and social behavior, comparisons between WS and ASD are still rare in the literature.

Childhood exposure to polybrominated diphenyl ethers and neurodevelopment at six years of age.

Mixtures of polybrominated diphenyl ethers (PBDEs) are present in indoor environments. Studies of the developmental effects of exposure to these chemicals in large prospective mother-child cohorts are required, with data on prenatal exposure and long-term follow-up of the children. We aimed to investigate the relationship between prenatal and childhood exposure to PBDEs and neurodevelopment at the age of six years.

Organophosphate Insecticide Metabolites in Prenatal and Childhood Urine Samples and Intelligence Scores at 6 Years of Age: Results from the Mother-Child PELAGIE Cohort (France).

Background: Several studies suggest that exposure to organophosphate insecticides (OP) during pregnancy impairs neurodevelopment in children.

Objectives: We evaluated associations between biomarkers of prenatal and postnatal OP exposure and cognitive function of 6-year-olds in a French longitudinal birth cohort.

Methods: In 2002-2006, the PELAGIE mother-child cohort enrolled pregnant women from Brittany.

Pyrethroid insecticide exposure and cognitive developmental disabilities in children: The PELAGIE mother-child cohort.

Pyrethroid insecticides are widely used in agriculture and in homes. Despite the neurotoxicity of these insecticides at high doses, few studies have examined whether lower-level exposures could adversely affect children's neurodevelopment. The PELAGIE cohort included 3421 pregnant women from Brittany, France between 2002 and 2006.

Inferring emotions from speech prosody: not so easy at age five.

Previous research has suggested that children do not rely on prosody to infer a speaker's emotional state because of biases toward lexical content or situational context. We hypothesized that there are actually no such biases and that young children simply have trouble in using emotional prosody. Sixty children from 5 to 13 years of age had to judge the emotional state of a happy or sad speaker and then to verbally explain their judgment.

Age- and sex-dependent contact call usage in Japanese macaques.

The question of the flexibility of nonhuman primate vocal communication remains open today, especially due to early evidence of innately guided vocal production. However, socially determined flexibility can be found when the debate is moved from vocal structure to vocal usage. While increasing evidence shows that the audience quality influences the vocal behaviour of nonhuman primates, the impact of the caller's characteristics has been far less studied.

Oral narrative skills in French adults who are functionally illiterate: linguistic features and discourse organization.

Purpose: To investigate the nature and extent of oral language difficulties encountered by adults who are functionally illiterate.

Method: Fifty-two men and women identified as functionally illiterate, together with a group of control individuals of comparable age, sex, and socioprofessional background, produced a narrative intended for an absent recipient based on a sequence of pictures featuring a cast of 3 protagonists. All narratives were transcribed in their entirety and coded in terms of linguistic features and discourse organization.

Idiom comprehension in French-speaking children and adolescents with Williams' syndrome.

This study looks at idiom comprehension by French-speaking people with Williams' syndrome (WS) and metapragmatic knowledge is examined. Idiomatic expressions are a nonliteral form of language where there is a considerable difference between what is said (literal interpretation) and what is meant (idiomatic interpretation). WS is characterized by a relatively preserved formal language, social interest and poor conversational skills.

Recognition of emotional and nonemotional facial expressions: a comparison between Williams syndrome and autism.

The aim of our study was to compare two neurodevelopmental disorders (Williams syndrome and autism) in terms of the ability to recognize emotional and nonemotional facial expressions. The comparison of these two disorders is particularly relevant to the investigation of face processing and should contribute to a better understanding of social behaviour and social cognition. Twelve participants with WS (from 6;1 to 15 years) and twelve participants with autism (from 4;9 to 8 years) were matched on verbal mental age.