Individual and combined effect of and gene polymorphisms in lung cancer.

Lung cancer (LC) is the second common and with the highest mortality oncological disease. Specific biomarkers for its diagnostics, treatment, and prognosis are still under the investigations. Aim of our study was to evaluate the relationship between the polymorphisms of TP53 pathway genes , , , the polymorphisms of HPV-associated genes , , , and HPV infection with survival of LC patients.