Publications by authors named "Aghdas Ramezani"
Interactions between the plasma cells and the BM microenvironment of Multiple myeloma (MM) take place through factors such as exosomes. Many studies have confirmed the role of exosomes in these interactions. By carrying proteins, cytokines, lipids, microRNAs, etc.
View Article and Find Full Text PDFIntroduction: Glial brain tumours are highly mortal and are noted as major neurosurgical challenges due to frequent recurrence or progression. Despite standard-of-care treatment for gliomas, the prognosis of patients with higher-grade glial tumours is still poor, and hence empowering antitumour immunity against glioma is a potential future oncological prospect. This review is designed to improve our understanding of the efficacy of cell-based immunotherapies for glioma.
View Article and Find Full Text PDFEtoposide (ETO), a popular anticancer drug that inhibits topoisomerase II enzymes, may be administered more effectively and efficiently due to nanomedicine. The therapeutic application of ETO is constrained by its limited solubility, weak absorption, and severe side effects. This article summarizes substantial progress made in the development of ETO nanomedicine for the treatment of cancer.
View Article and Find Full Text PDFCalcium-sensing receptor (CaSR), which is better known for its action as regulating calcium homeostasis, can bind various ligands. To facilitate research on CaSR and understand the receptor's function further, an in silico designed truncated protein was developed. The resulting protein folding indicated that 99% of predicted three dimensional (3D) structure residues are located in favored and allowed Ramachandran plots.
View Article and Find Full Text PDFArticle Synopsis
- The Xanthomonas genus typically cannot produce xanthan gum in lactose-based media due to low β-galactosidase expression.
- This study discovered that certain natural strains of Xanthomonas citri subsp. citri (Xcc) can utilize lactose as their only carbon source to successfully produce xanthan gum.
- Among the 210 strains isolated, NIGEBK37 was the most efficient, yielding 14.62 g/l of xanthan gum and showing the highest viscosity of 44,170.66 cP, highlighting the limitations of a commercial Xanthomonas strain in similar conditions.