Publications by authors named "Aggrey Kihombo"
On the cost-effectiveness of insecticide-treated wall liner and indoor residual spraying as additions to insecticide treated bed nets to prevent malaria: findings from cluster randomized trials in Tanzania.
Kihomo Robert Mpangala Yara A Halasa-Rappel Mohamed Seif Mohamed Ruth C Mnzava Kaseem J Mkuza Aggrey R Kihombo
BMC Public Health
September 2021
Article Synopsis
- Malaria remains a significant global health issue, with 409,000 deaths in 2019 despite efforts using long-lasting insecticidal nets (LLINs) and interventions like indoor residual spraying (IRS), which faces challenges like high costs and logistical complexities.
- A randomized controlled trial in Tanzania evaluated a new insecticide-treated wall liner (ITWL) to supplement LLINs, finding it initially improved coverage and lowered costs but ultimately failed to kill mosquitoes, leading to premature project termination.
- While the cost of ITWL was higher ($10.11 per person per year) compared to IRS ($5.69), IRS proved more effective in malaria prevention, with an incremental cost-effectiveness ratio (ICER) of $490 per disability-adjust
Background: Despite considerable reductions in malaria achieved by scaling-up long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), maintaining sustained community protection remains operationally challenging. Increasing insecticide resistance also threatens to jeopardize the future of both strategies. Non-pyrethroid insecticide-treated wall lining (ITWL) may represent an alternate or complementary control method and a potential tool to manage insecticide resistance.
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