Publications by authors named "Aggrey Adem"
Objectives: To determine the factors associated with poor outcomes among people living with HIV (PLHIV) started on anti- retroviral therapy before and after implementation of "Test and treat" program in 18 facilities in Coastal Kenya.
Methods: A retrospective cohort study design was used to study PLHIV aged > 15 years and started on ART in the periods of April to August 2016, and April to August 2017, then followed up for 24 months. Primary outcome was retention defined as being alive and on ARVs after 24 months.
Article Synopsis
- Alloreactive tumor-specific T cells play a crucial role in fighting tumors, with stem cell-like memory T cells (Tscm) being essential for effectively eliminating tumor cells.
- The study presents a new economical in vitro co-culture method to generate allo-restricted tumor-specific Tscm cells, aiming to improve accessibility for labs with fewer resources.
- Results indicate that the combination of rapamycin and IL-21 enhances the growth and maintenance of AFP-specific Tscm cells, suggesting a potential boost for cancer immunotherapy approaches.