Publications by authors named "Agenagnew Ashagre"

Background: Intestinal parasitic infections are a significant public health concern, especially among food handlers, who can transmit these infections to the public through food preparation and handling. This systematic review and meta-analysis aimed to determine the pooled prevalence and associated factors of intestinal parasitic infections among food handlers in the East African region.

Methods: A systematic review and meta-analysis on intestinal parasitic infections among food handlers involved a comprehensive search across various databases, including Scopus, PubMed, ScienceDirect, Google Scholar, and the institution's library registers.

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Background: Diabetes mellitus (DM) is a metabolic abnormality affecting 537 million people worldwide. Poor glycemic control, longer duration, and poor medication adherence increased the risk of DM complications. Comprehensive evidence on the pooled prevalence of microvascular complications in DM patients in Ethiopia is not available.

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Background: Infection with the hepatitis B virus (HBV) is still a major global public health concern, especially in Ethiopia. Evidence suggests that some children in Ethiopia who have received hepatitis B vaccinations are still contracting HBV.

Objective: The main aim of this study was to detect antibodies to hepatitis B core antigen (anti-HBc) among vaccinated hepatitis B surface antigen (HBsAg)-negative individuals in North-West Ethiopia.

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Malaria is a disease transmitted by vectors and caused by unicellular parasites. Malaria pathogenesis is associated with the ABO phenotype. However, there is little information on the frequency of malaria disease and its relationship with the ABO blood group in the study area.

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Article Synopsis
  • A systematic review and meta-analysis was conducted to estimate the prevalence of pulmonary tuberculosis (PTB) among key and vulnerable populations (KVPs) in hotspot regions of Ethiopia, despite a global decline in TB incidence.
  • The analysis included 34 articles, with methods involving data recorded and analyzed using STATA 17.0, assessing prevalence rates by various group settings and publication years.
  • The findings estimated a pooled PTB prevalence of 11.7% in hotspot settings, with specific prevalence rates for different KVPs: prison inmates (8.8%), university students (23.1%), refugees (28.4%), and others, highlighting significant vulnerability among these groups.
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Article Synopsis
  • - The study investigates the prevalence of carbapenem-resistant gram-negative bacteria that cause neonatal sepsis in African newborns, as this issue is a growing concern globally.
  • - A total of 36 research studies were analyzed, revealing a combined prevalence rate of 30.34% for carbapenem resistance among these bacteria in Africa.
  • - Specifically, A. baumannii and Pseudomonas species showed high resistance rates, with 45.9% and 43.0% prevalence, respectively, indicating a significant public health challenge.
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Background: Antimicrobial-resistant (AMR) bacterial infection is a significant global threat to the healthcare systems. Pseudomonas aeruginosa, the leading infectious agent in the healthcare setting is now one of the major threats due to AMR. A comprehensive understanding of the magnitude of AMR, particularly highly public health important pathogens such as P.

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Article Synopsis
  • * It found that 23.2% of participants had MetS, with significant associations between MetS and fasting blood glucose levels, alongside notable differences in cholesterol and blood pressure levels between H. pylori-positive and negative groups.
  • * The results highlight the importance of monitoring metabolic factors, as individuals with H. pylori infection exhibit distinct risk profiles in relation to MetS, suggesting a need for further research in this area.
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Background: Catheter-associated urinary tract infections (CAUTIs) account for the majority of device-associated healthcare-acquired infections with significant morbidity and mortality worldwide. In developing countries with limited resources, the burden of CAUTI have substantial burden owing to the lack of well-organized infection prevention and control. Although there are studies in African countries, the magnitude of CAUTI is inconsistent.

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