Publications by authors named "Agata Kosobucka-Ozdoba"
According to the ESC guidelines, cangrelor may be considered in P2Y12-inhibitor-naïve acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). The aim of this review is to summarize available evidence on the optimal maintenance therapy with P2Y12 receptor inhibitor after cangrelor. Transitioning from cangrelor to a thienopyridine, but not ticagrelor, can be associated with a drug-drug interaction (DDI); therefore, a ticagrelor loading dose (LD) can be given any time before, during, or at the end of a cangrelor infusion, while a LD of clopidogrel or prasugrel should be administered at the time the infusion of cangrelor ends or within 30 minutes before the end of infusion in the case of a LD of prasugrel.
View Article and Find Full Text PDFBackground: A chronic disease occurring in a person's life is a stressor, disrupting every aspect of their life.
Objectives: This study aims to assess the relationship between functioning in chronic illness and quality of life with the prevalence of symptoms of depression and anxiety in patients with high cardiovascular risk.
Material And Methods: This study included 200 patients (aged 18-80 years) under the care of a primary care physician, diagnosed with hypertension and/or hypercholesterolemia, and/or diabetes between 6 and 24 months before the enrollment.
Article Synopsis
- Elevated lipoprotein (a) [Lp(a)] levels are primarily influenced by genetics, and this study aimed to explore how these levels relate to other lipid disorders and cardiovascular (CV) risk factors.
- A cross-sectional analysis of 200 primary-care patients without known CV disease was performed, assessing various risk factors such as age, hypertension, diabetes, smoking, physical inactivity, body mass index (BMI), and specific lipid parameters.
- Results showed no significant differences in lipid parameters between patients with low (<30 mg/dL) and high (≥30 mg/dL) Lp(a) levels, but the high-Lp(a) group had a higher prevalence of previously diagnosed hyperlipidemia and lower rates of older age and
Background: Anxiety and depression by affecting lifestyle interfere with preventive actions aimed at eliminating or reducing modifiable risk factors for cardiovascular diseases (CVD).
Purpose: The objective of the study was to assess the impact of anxiety and depression on the achievement of therapeutic goals regarding CVD risk factors in patients without a history of atherosclerotic CVD.
Patients And Methods: The study included 200 patients (median age 52.
Post-COVID-19 syndrome (PCS) may affect a substantial proportion of patients who have had COVID-19. The rehabilitation program might improve the physical capacity, functioning of the cardiopulmonary system, and mental conditions of these patients. This study aimed to investigate the effectiveness of personalized rehabilitation in patients with PCS according to gender.
View Article and Find Full Text PDF(1) Background: Eliminating or reducing the severity of modifiable risk factors of cardiovascular disease (CVD) and undertaking health-promoting behaviors is the basis for prevention. (2) Methods: This study included 200 subjects without a history of CVD, aged 18 to 80 years, who had been diagnosed with hypertension, hypercholesterolemia, or diabetes 6 to 24 months before study enrolment. (3) Results: The median 10-year CV risk assessed by the SCORE2 and SCORE2-OP algorithms was 3.
View Article and Find Full Text PDFTo assess the determinants of lipid parameters in primary care patients without diagnosed cardiovascular disease (CVD), a cross-sectional study was conducted during 2018-2019 with a total of 200 patients. The following lipid parameters were measured: total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), small, dense LDL (sdLDL-C), and lipoprotein (a) (Lp(a)). Predictors of elevated and adequately controlled lipid parameters were assessed with logistic regression analysis.
View Article and Find Full Text PDFArticle Synopsis
- Up to 80% of COVID-19 survivors experience long-term symptoms known as long COVID-19, prompting a study on the effects of a multidisciplinary rehabilitation program.
- The program involved physical training, education, and group psychotherapy, leading to significant improvements in body composition, with reduced abdominal fat and increased muscle mass.
- Nearly 80% of participants reported less breathlessness, enhanced physical capacity, and decreased fatigue after 6 weeks of rehabilitation, although cardiopulmonary exercise test results showed no change.
The aim of this study was to determine anti-SARS-CoV-2 IgG concentrations and their major determinants in healthcare workers (HCWs) after full vaccination with the BNT162b2 vaccine. We recruited 847 individuals vaccinated with two doses of the BNT162b2 vaccine, who completed the questionnaire, and whose antibody concentrations were tested after 3 and 6 months after full vaccination. Anti-SARS-CoV-2 IgG levels were measured on the routinely employed Siemens Atellica system.
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