Immune Priming Promotes Thermotolerance, Whereas Thermopriming Suppresses Systemic Acquired Resistance in Arabidopsis.

Heat stress and pathogens are two serious yield-limiting factors of crop plants. Plants that previously experienced high but sub-lethal temperatures become subsequently tolerant to higher temperatures through the development of acquired thermotolerance (ATT). ATT activation is associated with the elevated expression of heat shock (HS)-related genes such as HSFA2, HSFA3, and HSP101.

Present and Future Use of Exosomes in Dermatology.

Exposure to external environmental stimuli can lead to skin aging, pigmentation, hair loss, and various immune-mediated as well as connective tissue diseases. Although conventional treatments are routinely used and favoured, they fail to achieve an adequate balance between clinical and cosmetic outcomes. Exosomes are vesicles with a lipid bilayer released by several cell types.

Two new species of South Asian Cnemaspis Strauch, 1887 (Squamata: Gekkonidae) from the far northern peaks of the Western Ghats, India.

We describe two new species of South Asian Cnemaspis from far northern peaks of the Northern Western Ghats of Maharashtra, India. The two new species are the most northernly distributed representatives of the girii clade and are phylogenetically and morphologically allied to C. uttaraghati.

Five new species of the Cnemaspis beddomei clade (Squamata: Gekkonidae) from high elevation, evergreen forests of the Southern Western Ghats, India.

We describe five new species allied to Cnemaspis beddomei from the Southern Western Ghats, Tamil Nadu, India using morphological data and mitochondrial sequence divergence. The new species are members of the beddomei and anamudiensis subclades within the beddomei clade and are from boulder habitats in evergreen forests in Tenkasi (Cnemaspis tenkasiensis sp. nov.

A new small-sized Calotes Cuvier (Squamata: Agamidae: Draconinae) from the Subansiri river basin, Arunachal Pradesh, India.

We describe a new species of small-sized Calotes from mid-elevation (~1270 m asl.), swidden or shifting cultivation areas in the Subansiri river basin, Upper Subansiri District, Arunachal Pradesh, India. Mitochondrial sequence data (ND2) recovers Calotes sinyik sp.

Two new nocturnal species of South Asian Cnemaspis Strauch, 1887 (Squamata: Gekkonidae) of the wynadensis clade from the southern Western Ghats, India.

We describe two new medium-bodied, nocturnal species of South Asian Cnemaspis from the southern Western Ghats, Tamil Nadu, India in an integrative taxonomic framework. The two new species are phylogenetically and morphologically allied to the wynadensis clade and can be distinguished from other species of the wynadensis clade and each other by a combination of nonoverlapping morphological characters including body size, homogeneous dorsal pholidosis, the number of femoral pores and poreless scales separating these series, the number of ventral scales across the midbody and longitudinal scales from mental to cloaca, the number of dorsal granules around the body; and an uncorrected pairwise ND2 sequence divergence of 8.2-22.

A preliminary taxonomic revision of the girii clade of South Asian Cnemaspis Strauch, 1887 (Squamata: Gekkonidae) with the description of four new species from southern Maharashtra, India.

The girii clade is the most diverse clade of South Asian Cnemaspis in the Northern Western Ghats, including ten valid species. Recent collections of four divergent lineages from southern Maharashtra prompted us to examine the type material of all species in the girii clade, which led to the discovery of numerous errors and discrepancies in the literature. We take this opportunity to provide an updated and expanded morphological dataset including diagnoses and comparisons for all species of the girii clade and to build an almost complete species-level phylogeny including the first ND2 sequences of C.

Report of stray sightings of Dendrelaphis proarchos (Wall, 1909) (Serpentes: Colubridae) in Surat, Gujarat, western India.

We here report on likely human-mediated, stray sightings of Dendrelaphis proarchos (Wall, 1909) in an unnatural range-Surat, Gujarat in western India. This population shows the following characters: (1) vertebral scales distinctly enlarged, larger than the dorsals of the first row; (2) 185-194 ventrals; (3) 139-142 divided subcaudals in complete tails; (4) 15 dorsal scale rows at midbody; (5) cloacal shield undivided; (6) one loreal scale; (7) three supralabials touching the eye; (8) a moderate first sublabial that touches two infralabials; (9) 11-12 temporal scales; (10) preoculars 1 or 2; (11) two or three postoculars; (12) maximum total length 1150 mm; (13) interparietal spot absent; (14) a black temporal stripe that does not starts on the postnasal or loreal but starts on the center of the eye follows postoculars (middle or second postocular) covers the majority of the temporal region and extends onto the neck; (15) a distinct, bright ventrolateral stripe bordered by one black line at the bottom; (16) dorsal interstitial color blue and (17) tongue color red with black tip. Data from a partial fragment of the mitochondrial 16S gene also reveal genetic congruence with published sequences from Sagaing and Ayeyarwady in Myanmar and Mizoram, India, further attesting the morphological conclusions.

Entrustable professional activities (EPAs) in surgical pathology: implementation experience and longitudinal observations of resident development.

Entrustable professional activities (EPAs) have been implemented in various medical specialties, and the Pathology National EPA Working Group has piloted the implementation of four pathology EPAs. We recently published the development of EPAs within our surgical pathology rotation. Following a six-month pilot, a survey demonstrated that faculty and residents found the forms helpful and easy to use and easy to understand, and EPAs have been fully incorporated into our surgical pathology rotation.

Exposure to Mycophenolic Acid and Its Clinical Response in an Indian Pediatric Population with Nephrotic Syndrome.

Background: Children with nephrotic syndrome experience many side effects and frequent relapses when treated with steroids and other drugs. Mycophenolic acid (MPA) is one of the effective and least toxic drug for the treatment of nephrotic syndrome. This drug needs to be monitored for maximal efficacy and minimal toxicity.

Refinement of cryo-EM 3D maps with a self-supervised denoising model: crefDenoiser.

Cryogenic electron microscopy (cryo-EM) is a pivotal technique for imaging macromolecular structures. However, despite extensive processing of large image sets collected in cryo-EM experiments to amplify the signal-to-noise ratio, the reconstructed 3D protein-density maps are often limited in quality due to residual noise, which in turn affects the accuracy of the macromolecular representation. Here, crefDenoiser is introduced, a denoising neural network model designed to enhance the signal in 3D cryo-EM maps produced with standard processing pipelines.

ChaQra: a cellular unit of the Indian quantum network.

Major research interests on quantum key distribution (QKD) are primarily focused on increasing 1. Point-to-point transmission distance (1000 km). 2.

Validation Study of the Newly Proposed Refined Diagnostic Criteria for Malignant Phyllodes Tumor With 136 Borderline and Malignant Phyllodes Tumor Cases.

The World Health Organization (WHO) diagnostic criteria for malignant phyllodes tumor (MPT) may miss a significant number of MPTs with metastatic potential. New refined diagnostic criteria (Refined Criteria) for MPT were recently proposed. The aim of this study is to validate the Refined Criteria.

Threat-dependent scaling of prelimbic dynamics to enhance fear representation.

Promptly identifying threatening stimuli is crucial for survival. Freezing is a natural behavior displayed by rodents toward potential or actual threats. Although it is known that the prelimbic cortex (PL) is involved in both risk evaluation and in fear and anxiety-like behavior expression, here we explored whether PL neuronal activity can dynamically represent different internal states of the same behavioral output (i.

Scrub typhus in pregnancy: A report of two cases.

Scrub typhus shows a high prevalence in South-East Asia. In pregnant females, it can cause both maternal and fetal adverse outcomes. We report a case series of two women with scrub typhus and their varied outcomes.

Replicator-mutator dynamics of the rock-paper-scissors game: Learning through mistakes.

We generalize the Bush-Mosteller learning, the Roth-Erev learning, and the social learning to include mistakes, such that the nonlinear replicator-mutator equation with either additive or multiplicative mutation is generated in an asymptotic limit. Subsequently, we exhaustively investigate the ubiquitous rock-paper-scissors game for some analytically tractable motifs of mutation pattern for which the replicator-mutator flow is seen to exhibit rich dynamics that include limit cycles and chaotic orbits. The main result of this paper is that in both symmetric and asymmetric game interactions, mistakes can sometimes help the players learn; in fact, mistakes can even control chaos to lead to rational Nash-equilibrium outcomes.

Racial differences in triage assessment at rural vs urban Maine emergency departments.

Data continue to accumulate demonstrating that those belonging to racialized groups face implicit bias in the emergency care delivery system across many indices, including triage assessment. The Emergency Severity Index (ESI) was developed and widely implemented across the US to improve the objectivity of triage assessment and prioritization of care delivery; however, research continues to support the presence of subjective bias in triage assessment. We sought to assess the relationship between perceived race and/or need for translator and assigned ESI score and whether this was impacted by hospital geography.

Comparison of Various Commonly Used Luting Cements on the Success of Composite Inlays Assessed by the Levels of the Microleakage-An Study.

Introduction: Indirect composite restoration is one of the commonly followed procedures in the posterior teeth. The success of this is dependent on many factors, one being the luting cement. Hence, the current study explores the microleakage of the two luting cements at 2 different times.

Two new species of the complex (Squamata, Gekkonidae) from the eastern slopes of the southern Western Ghats.

Two new species allied to are described from the eastern slopes of the south Western Ghats, Tamil Nadu, India. Both new species are members of the subclade within the clade. The two new species can be easily distinguished from all other members of the clade and each other by a combination of nonoverlapping morphological characters such as small body size, distinct colouration of both sexes, the number of dorsal tubercles around the body, the number or arrangement of paravertebral tubercles, the number of midventral scales across the belly and longitudinal ventral scales from mental to cloaca, besides uncorrected pairwise ND2 and 16S sequence divergence of ≥ 7.

Sustained Pericarditis Recurrence Risk Reduction With Long-Term Rilonacept.

Background: Rilonacept, a once-weekly interleukin-1 alpha and beta cytokine trap, reduced pericarditis recurrence in the phase 3 study, RHAPSODY (Rilonacept Inhibition of Interleukin-1 Alpha and Beta for Recurrent Pericarditis: A Pivotal Symptomatology and Outcomes Study). The RHAPSODY long-term extension further explored recurrent pericarditis natural history and treatment duration decision-making during 24 additional months of open-label rilonacept treatment.

Methods And Results: Seventy-four patients commenced the long-term extension, with a median (maximum) total rilonacept duration of 22 (35) months.

The Clinical Profile and Long-Term Outcome of Children with Membranous Nephropathy, and the Evaluation of Anti-Phospholipase A2 Receptor Antibody Immunohistochemistry in Kidney Biopsy.

Introduction: Idiopathic membranous nephropathy (iMN) is a rare cause of nephrotic syndrome in children (1%-7%). Anti-phospholipase A2 receptor (PLAR) antibody positivity in kidney biopsy is observed in 52%-78% of adults and 45% of children with iMN. The objectives of the study are to analyze the clinical profile and outcome of membranous nephropathy in children, to assess the prevalence of anti-PLAR immunohistochemistry (IHC) in kidney biopsy, and to correlate their presence with disease characteristics.

Seeking Safety for women in incarceration: a systematic review.

Purpose: Seeking Safety is an evidence-based treatment for individuals with comorbid posttraumatic stress disorder and substance use disorder. This treatment shows promise to address the unique, unmet needs of women in prison. The current systematic literature review aims to highlight several critical gaps in research on Seeking Safety in forensic settings that need to be filled before Seeking Safety can be implemented in a widespread manner.