Guar gum (GG), as a non-exudate gum, is extracted from the seed's embryos of Cyamopsis tetragonoloba (a member of Leguminosae family). Recently, this biopolymer has received extensive attention due to its low cost, notable properties, non-toxic biodegradation, ease of availability, and biocompatibility. However, disadvantages such as uncontrolled hydration rate and susceptibility to microbial attack have led many researchers to further modification of guar gum.
View Article and Find Full Text PDFGelatin-based biomaterials are widely acknowledged as a promising choice for wound dressings, given their similarity to the extracellular matrix and biocompatibility. However, the challenge of cross-linking gelatin while preserving its biocompatibility and cost-effectiveness persists. This study aimed to enhance the properties of gelatin by incorporating the oxidized lignosulfonate (OLS) biopolymer as an inexpensive and biocompatible natural material.
View Article and Find Full Text PDFPlant-based hard capsules have gained considerable attention because of their great properties. Accordingly, designing and developing of these kinds of capsules will be a difficult task. Herein, an innovative pullulan-based hard capsule formulation was prepared for the first time.
View Article and Find Full Text PDFCapsules are popular oral dosage forms because of their ease of production. They are widespread pharmaceutical products. Hard capsules are preferred dosage forms for new medicines undergoing clinical tests because they do not require expansive formulation development.
View Article and Find Full Text PDFInt J Biol Macromol
February 2023
One of the most vital aspects of the orthopedic implant field has been the development of multifunctional coatings that improve bone-implant contact while simultaneously preventing bacterial infection. The present study investigates the fabrication and characterization of multifunctional polysaccharides, including carboxymethyl cellulose (CMCn) and carboxymethyl chitosan nanofibers (CMCHn), as a novel implant coating on titania nanotube arrays (T). Field emission scanning electron microscopy (FESEM) images revealed a nanofibrous morphology with a narrow diameter for CMCn and CMCHn, similar to extracellular matrix nanostructures.
View Article and Find Full Text PDFSuitable wound dressings for accelerating wound healing are actively being designed and synthesised. In this study, thiolated chitosan (tCh)/oxidized carboxymethyl cellulose (OCMC) hydrogel containing Cu-doped borate bioglass (BG) was developed as a wound dressing to improve wound healing in a full-thickness skin defect of mouse animal model. Thiolation was used to incorporate thiol groups into chitosan (Ch) to enhance its water solubility and mucoadhesion characteristics.
View Article and Find Full Text PDFFor the first time, a bio-photo-catalyst is synthesized in a microfluidic platform. The microchannel, which is wall-coated by in situ synthesized bio-photo-catalyst is used as an opto-fluidic reactor for amoxicillin degradation. Analyses including SEM, XRD, FTIR, Raman, UV-Vis spectra, and DLS have been used to characterize samples.
View Article and Find Full Text PDFMotor neuron diseases such as spinal cord injuries and amyotrophic lateral sclerosis are known as the most common disorders worldwide. Using stem cells (e.g.
View Article and Find Full Text PDFThe present work reviews recent developments in plant cellulose-based biomaterial design and applications, properties, characterizations, and synthesis for skin tissue engineering and wound healing. Cellulose-based biomaterials are promising materials for their remarkable adaptability with three-dimensional polymeric structure. They are capable of mimicking tissue properties, which plays a key role in tissue engineering.
View Article and Find Full Text PDFBacterial cellulose (BC) was produced via the static fermentation process using G. xylinus. Cellulose and diethylaminoethyl cellulose (DEAEC) were converted to carboxymethyl cellulose (CMC) and carboxymethylated diethylaminoethyl cellulose (CMDEAEC) while to prepare the composites, two different methods were used: by either direct addition of the materials to the fermentation medium or addition of the materials after the fermentation process.
View Article and Find Full Text PDFDue to the unique properties of cellulose-based materials, they are attractive to be developed in industrial pharmaceutics and biomedical fields. Carboxymethyl-diethyl amino ethyl cellulose scaffold (CM-DEAEC) has been synthesized in the current work as a smart novel derivative of cellulose with a great functionality in drug delivery systems. The scaffolds were well cross-linked with 2% (v/v) epichlorohydrin (ECH), loaded with curcumin (Cur), and then were analyzed by FT-IR, XRD, SEM, and mechanical strength.
View Article and Find Full Text PDFWastewater effluents usually involve dyes that are dangerous for aquatic life and other environments. Many of these dyes are toxic, carcinogenic, and can cause skin and eye irritation. In this study, firstly aminized cellulose acetate was prepared from cellulose acetate and applied for the adsorption of Acid Brown 354 from aqueous solutions.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
December 2020
We reported a novel dual-emission fluorescence probe fabricated by encapsulating both gold (AuNCs) and copper nanoclusters (CuNCs) into zeolitic imidazolate framework-8 (ZIF-8). Obtained composite (AuCuNCs@MOF) was utilized for ratiometric determination of Tetracycline (Tcy) antibiotic. Under excitation at 400 nm, the AuCuNCs@MOF composite displayed two emission peaks at 520 and 650 nm which were originated from AuNCs and CuNCs, respectively.
View Article and Find Full Text PDFCellulose based microcarriers can be used in biomedical science as supports for cell adhesion and proliferation. However, to facilitate cell attachment to their surface, they require appropriate functional surface charge. Cell function such as adhesion and growth is increased on the modified surfaces with cationic and anionic groups.
View Article and Find Full Text PDFThe aim of this study was to modify surface properties of immobilized rutile TiO₂ using Argon cold plasma treatment and to evaluate the performance of the catalyst in photocatalytic elimination of synthetic dyes in UV/TiO₂/H₂O₂ process. The surface-modified TiO₂ was characterized by XRD, EDX, SEM, UV-DRS and XPS analyses. Response surface methodology was adopted to achieve high catalyst efficiency by evaluating the effect of two main independent cold plasma treatment parameters (exposure time and pressure) on surface modification of the catalyst.
View Article and Find Full Text PDFFabrication and characterization of different surface charged cellulose electrospun scaffolds including cellulose acetate (CA), cellulose, carboxymethyl cellulose (CMC) and quaternary ammonium cationic cellulose (QACC) for biomedical applications have been reported in this research. Several instrumental techniques were employed to characterize the nanofibers. MTT assay and cell attachment studies were also carried out to determine the cytocompatibility, viability and proliferation of the scaffolds.
View Article and Find Full Text PDFIn the present research the optimization of ultrasound-mediated production of carboxymethyl cellulose under microwave irradiation, towards achieving reduction of chemicals, time of reaction and energy was carried out. Cellulose was extracted and treated by environmentally friendly chlorine free bleaching method using hydrogen peroxide. Produced alpha-cellulose was characterized using Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM) and thermogravimetric/differential thermal analysis (TG/DTA).
View Article and Find Full Text PDFScientificWorldJournal
October 2012
An enzymatic reaction using glucose oxidase was applied for in situ production of hydrogen peroxide for use in simultaneously Fenton's reaction in decolorization of malachite green. It was found that decolorization rate increased by increasing of glucose concentration from 0.2 g/L to 1.
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