Publications by authors named "Aftab Yaseen"

In this study, the response surface method (RSM) was used to determine the optimal parameters of ultrasonic-assisted extraction of Gymnocladus chinensis Baill. polysaccharides (GCBPs). The optimal extraction conditions were as follows: a liquid-solid ratio of 50.

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Background: Environmental stresses pose a significant threat to plant growth and ecosystem productivity, particularly in arid lands that are more susceptible to climate change. Strigolactones (SLs), carotenoid-derived plant hormones, have emerged as a potential tool for mitigating environmental stresses.

Methods: This review aimed to gather information on SLs' role in enhancing plant tolerance to ecological stresses and their possible use in improving the resistance mechanisms of arid land plant species to intense aridity in the face of climate change.

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Steroidal alkaloids (1-11), including one new 24-hydroxylated cevanine-type steroidal alkaloid, named yibeinone F (1), were isolated from the bulbs of Fritillaria pallidiflora Schrenk. Their structures were elucidated by analyses of extensive spectroscopic data and comparison of the NMR data with those reported previously, and the structures of compounds 1, 7 and 11 were further confirmed by X-ray single crystal diffraction analyses. The anti-inflammatory effects of all the isolated alkaloids were evaluated in LPS-activated RAW264.

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Seven undescribed terpenoids, including three pairs of enantiomers, named (±)-rugulolides A-C, and one cyclopentenone derivative, named rugulolide D, together with twenty-six known compounds, were isolated from the aerial parts of Elsholtzia rugulosa. The chiral separation of rugulolides A-C was achieved by high-performance liquid chromatography using the chiral column. Their structures were elucidated unambiguously based on comprehensive spectroscopic analysis in conjunction with electronic circular dichroism (ECD) and single-crystal X-ray diffraction experiments.

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In current study, we studied the phytochemicals of (fruits) in which we identify twenty compounds, including two coumarins ( and ), three coumestans (-), fourchalcone (-), three dihydroflavones (-), four isoflavones (-), one flavonoid () and three meroterpenes (-). Among these, compounds , and were isolated from for the first time. The ferroptosis inhibitory effects of the isolated phytochemicals were assessed using erastin-exposed HT22 mouse hippocampal cells.

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Article Synopsis
  • The study investigates ginsenosides, bioactive compounds found in the leaves and roots of a certain plant, noting their different medicinal properties due to distinct chemical compositions.
  • Researchers isolated two novel ginsenosides, ginsenoside LS and 5,6-didehydroginsenoside Rg, using advanced techniques and evaluated their anti-inflammatory effects on specific immune cells.
  • The results indicate that one of the compounds showed a strong ability to inhibit inflammation markers and could be a promising candidate for medicinal applications or functional foods, with further research suggested to explore its mechanisms.
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Two novel cucurbitane glycosides, named as 11-oxomogroside III A and 7β-methoxy-mogroside V, along with sixteen known ones were isolated from the fruits of Siraitia grosvenori SWINGLE. The structures of the new compounds were characterized by chemical and extensive spectral methods.

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Senkyunolide H (SNH) is a phthalide isolated from the rhizome of Ligusticum chuanxiong Hort. that has been reported to have several pharmacological activities, including anti-atherosclerotic, antiproliferative, and cytoprotective effects. In this study, we investigated the neuroprotective effects and potential mechanisms of SNH against 1-methyl-4-phenylpyridinium (MPP)-induced oxidative stress.

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