Dietary inclusion of black soldier fly (Hermetia illucens) larvae meal, with exogenous protease supplementation, in practical diets for striped catfish (Pangasius hypophthalmus, Sauvage 1878).

Fishmeal (FM) is a key component of commercial fish feeds, but due its unsustainable supply, the search for quality alternatives of FM has become a significant area of investigation worldwide. The insect-based proteins such as black soldier fly larvae (BSFL) are being recognized as an alternative ingredient. However, anti-nutritional factors in these alternatives may negatively affect nutrient utilization in fish.

Dural Venous Sinus Thrombosis: A Rare Cause of Intracranial Hemorrhage.

Dural venous sinus thrombosis, a subset of cerebral venous thrombosis, is an important pathology due to its significant morbidity and mortality. This process has an annual incidence of three to five cases per million adults. Although copious predisposing factors exist, the core principles revolve around Virchow's triad: venous stasis, hypercoagulability, and vascular endothelial damage.

Enhancing motor imagery EEG signal decoding through machine learning: A systematic review of recent progress.

This systematic literature review explores the intersection of neuroscience and deep learning in the context of decoding motor imagery Electroencephalogram (EEG) signals to enhance the quality of life for individuals with motor disabilities. Currently, the most used non-invasive method for measuring brain activity is the EEG, due to its high temporal resolution, user-friendliness, and safety. A Brain Computer Interface (BCI) framework can be made using these signals which can provide a new communication channel to people that are suffering from motor disabilities or other neurological disorders.

Growth Differentiation Factor-15 versus Human Chorionic Gonadotropin in Pathophysiology of Nausea and Vomiting of Pregnancy.

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Physical and mechanical characterizations of experimental pit and fissure sealants based on bioactive glasses.

Fissure sealants commonly exhibit weak mechanical and physical properties, potentially compromising their effectiveness in preventing dental caries. Therefore, this laboratory study aimed to synthesize and characterize experimental pit and fissure sealants in comparison with a commercially available sealant. Three different formulations of experimental pit and fissure sealing materials were synthesized using a blend of bisphenol A-glycidyl methacrylate (Bis-GMA) and triethylene glycol dimethacrylate (TEGDMA) monomers.

A National Survey on Congenital Hypothyroidism Newborn Screening in Pakistan.

. Congenital hypothyroidism (CH) is a treatable condition with a good outcome if diagnosed promptly. However, neonatal screening programs are not routinely available in developing countries in Pakistan.

Intersection of Care: Navigating Patient-Hospital Relationships in Neurosurgery.

Background: This study explores the vital elements of patient satisfaction in hospital settings, with an emphasis on the aspects of service quality and patient-hospital interaction. It looks at how patients perceive several aspects of service quality, such as assurance, tangibility, empathy, responsiveness, and consistency.

Methods: A descriptive cross-sectional study was conducted among 80 neurosurgery in-patients at the Pakistan Institute of Medical Sciences, using convenience sampling.

Exploring Nanoscale Perovskite Materials for Next-Generation Photodetectors: A Comprehensive Review and Future Directions.

The rapid advancement of nanotechnology has sparked much interest in applying nanoscale perovskite materials for photodetection applications. These materials are promising candidates for next-generation photodetectors (PDs) due to their unique optoelectronic properties and flexible synthesis routes. This review explores the approaches used in the development and use of optoelectronic devices made of different nanoscale perovskite architectures, including quantum dots, nanosheets, nanorods, nanowires, and nanocrystals.

Submandibular Gland Preservation in Oral Cavity Squamous Cell Carcinomas: Our Analysis at A Tertiary Care Hospital.

Introduction: Surgical excision forms the principal treatment of oral cavity squamous cell carcinomas. The comprehensive surgical management consists of Wide Local Excision of the tumor and Neck Dissection with removal of Submandibular gland. The submandibular gland accounts for 70-90 % of unstimulated salivary volume.

Enhancement of Electron Transport Characteristics Using MXene-MnFeO Nanocomposite Integration with Fullerene Derivatives for the Perovskite-Based Solar Cells and Detectors.

In this study, we prepared a hybrid film incorporating the MnFeO-decorated conducting two-dimensional (2D) MXene sheet-suspended [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) electron transfer layer (ETL) for the perovskite solar cells (PSCs) and detectors. The incorporation of MXene-MnFeO with the PCBM ETL could drive exceptional conducting features for the PSCs. Moreover, the presence of MXene-MnFeO facilitated superior charge transfer pathways, thereby enhancing the electron extraction and collection processes.

Laser-Induced Graphene for Advanced Sensing: Comprehensive Review of Applications.

Laser-induced graphene (LIG) and Laser-scribed graphene (LSG) are both advanced materials with significant potential in various applications, particularly in the field of sustainable sensors. The practical uses of LIG (LSG), which include gas detection, biological process monitoring, strain assessment, and environmental variable tracking, are thoroughly examined in this review paper. Its tunable characteristics distinguish LIG (LSG), which is developed from accurate laser beam modulation on polymeric substrates, and they are essential in advancing sensing technologies in many applications.

Diabetes and mutation; are they really linked together?

Objectives: We are reporting a rare case series of 2 siblings and their mother with diabetes having a gene mutation.

Case Presentation: Two female siblings, presented with incidental hyperglycemia at the ages of 16 and 13. They had a strong family history of diabetes on the maternal side.

Use of Myo-Inositol Vaginal Pessary in the Treatment of Subfertility.

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Managing Children and Adolescents with Type 1 Diabetes and Coexisting Celiac Disease: Real-World Data from a Global Survey.

Introduction: Celiac disease (CD) is among the diseases most commonly associated with type 1 diabetes (T1D). This study aimed to evaluate the worldwide practices and attitudes of physicians involved in pediatric diabetes care regarding diagnosing and managing CD in children with T1D.

Methods: The 30-item survey was conducted between July and December 2023 aimed at targeting pediatricians with special interest in T1D and CD.

MX MXenes: Application in Energy Storage Devices.

MXene has garnered widespread recognition in the scientific community due to its remarkable properties, including excellent thermal stability, high conductivity, good hydrophilicity and dispersibility, easy processability, tunable surface properties, and admirable flexibility. MXenes have been categorized into different families based on the number of M and X layers in MX, such as MX, MX, MX, and, recently, MX. Among these families, MX and MX, particularly TiC, have been greatly explored while limited studies have been given to MX MXene synthesis.

Gene expression and anticancer evaluation of Kigelia africana (Lam.) Benth. Extracts using MDA-MB-231 and MCF-7 cell lines.

In recent years, a cancer research trend has shifted towards identifying novel therapeutic compounds from natural assets for the management of cancer. In this study, we aimed to assess the cytotoxic activity of Kigelia Africana (KA) extracts on breast cancer (MDA-MB-231 and MCF-7) and noncancerous kidney cells (HEK-293T) to develop an efficient anticancer medication. We used gas chromatography mass spectrometry (GC-MS to analyze the constituents of EKA and HKA extracts meanwhile the crystal violet and the MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide) assays were used to examine the possible cytotoxic effects of plant extracts on our cancer cell lines along with non-cancerous control.

Safety of tranexamic acid in surgically treated isolated spine trauma.

Background: Tranexamic acid (TXA), a synthetic antifibrinolytic drug, effectively reduces blood loss by inhibiting plasmin-induced fibrin breakdown. This is the first study in the United Kingdom to investigate the effectiveness of TXA in the surgical management of isolated spine trauma.

Aim: To assess the safety of TXA in isolated spine trauma.

Silencing RNA-Mediated Knockdown of IFITM3 Enhances Senecavirus A Replication.

Senecavirus A (SVA) is a non-enveloped, positive sense, single-stranded RNA virus that causes vesicular diseases in pigs. Interferon-induced transmembrane 3 (IFITM3) is an interferon-stimulated gene (ISG) that exhibits broad antiviral activity. We investigated the role of IFITM3 in SVA replication.

Offloading the computational complexity of transfer learning with generic features.

Deep learning approaches are generally complex, requiring extensive computational resources and having high time complexity. Transfer learning is a state-of-the-art approach to reducing the requirements of high computational resources by using pre-trained models without compromising accuracy and performance. In conventional studies, pre-trained models are trained on datasets from different but similar domains with many domain-specific features.

Lupus Vasculitis.

We present the case of a 30-year-old woman who presented with 8-month history of intermittent fever, joint pains with morning stiffness, recurrent oral ulcers, photosensitivity, weight loss and hair fall. For the last 2 months, she had developed a dry cough with progressive shortening of breath. On examination, a cachexic lady with malar hyperpigmentation, alopecia, pallor, nail dystrophy and erythema over her hands and feet were noted.

Formulation of Hierarchical Nanowire-Structured CoNiO and MoS/CoNiO Hybrid Composite Electrodes for Supercapacitor Applications.

Hierarchical porous nanowire-like MoS/CoNiO nanohybrids were synthesized via the hydrothermal process. CoNiO nanowires were selected due to the edge site, high surface/volume ratio, and superior electrochemical characteristics as the porous backbone for decoration of layered MoS nanoflakes to construct innovative structure hierarchical three-dimensional (3D) porous NWs MoS/CoNiO hybrids with excellent charge accumulation and efficient ion transport capabilities. Physicochemical analyses were conducted on the developed hybrid composite, revealing conclusive evidence that the CoNiO nanowires have been securely anchored onto the surface of the MoS nanoflake array.