Efficacy of radiation therapy in the local control of desmoplastic malignant melanoma.

Background: Desmoplastic malignant melanoma (DMM) is a rare variant of malignant melanoma with high local recurrence rate after surgical excision. We performed a retrospective review to address the role of radiation therapy in local control of this tumor.

Methods: Between 1976 and 1997, 44 patients with the pathologic diagnosis of DMM were registered at our tumor registry.

The role of radiation in the treatment of advanced juvenile angiofibroma.

Objectives/hypothesis: To demonstrate the efficacy of external beam radiation therapy as a primary treatment modality for the management of patients with advanced juvenile nasopharyngeal angiofibroma (JNA).

Study Design: Retrospective chart review.

Methods: The medical records of 130 patients with the diagnosis of JNA seen at UCLA Medical Center over a 41-year period (1960-2000) were retrospectively reviewed.