Publications by authors named "Afshan Saleem"
Biogeographic variations in the gut microbiota are pivotal to understanding the global pattern of host-microbiota interactions in prevalent lifestyle-related diseases. Pakistani adults, having an exceptionally high prevalence of type 2 diabetes mellitus (T2D), are one of the most understudied populations in microbiota research to date. The aim of the present study is to examine the gut microbiota across individuals from Pakistan and other populations of non-industrialized and industrialized lifestyles with a focus on T2D.
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- The study focuses on the need for extensive research on human papilloma virus (HPV) and its link to head and neck squamous cell carcinomas (HNSCC), aiming to understand the impact, treatment advancements, and associated challenges globally.
- It highlights the difference between HPV-related HNSCC and other cancers, noting HPV's immune response may increase patient survival, but raises concerns about future neurogenic disorders as it can be transmitted to future generations.
- After reviewing 300 articles, 24 studies met the criteria, revealing the highest HPV prevalence in South Asia (10.42%), particularly HPV genotype-16, while the data was limited or lacking for central Asia.