Expression and Function of Long-Noncoding RNA in Breast Cancer Cell Lines and Tissues.

miR-29b2 and miR-29c play a suppressive role in breast cancer progression. (also named ) is the host gene for generating both microRNAs. However, the region also expresses longer transcripts with unknown functions.

Enrichment of A Rare Subpopulation of miR-302-Expressing Glioma Cells by Serum Deprivation.

Objective: MiR-302-367 is a cluster of polycistronic microRNAs that are exclusively expressed in embryonic stem (ES) cells. The miR-302-367 promoter is functional during embryonic development but is turned off in later stages. Motivated by the cancer stem cell hypothesis, we explored the potential expression of miR-302 in brain tumor cell lines.

Differential expression of nucleostemin, a stem cell marker, and its variants in different types of brain tumors.

Nucleostemin (NS) is implicated in the control of stem and cancer cell proliferation. In the present study, we have examined the expression of NS and its spliced variants in various brain tumors. Total RNA was extracted from 59 brain tumor samples, and the expression of different NS spliced variants was measured by semi-quantitative RT-PCR.

Overexpression of BMI1, a polycomb group repressor protein, in bladder tumors: a preliminary report.

Introduction: A Polycomb group repressor protein named BMI1 represses the genes that induce cellular senescence and cell death, and it can contribute to cancer when improperly expressed. We aimed to evaluate expression of BMI1 gene in bladder tumors.

Materials And Methods: Tissue specimens containing bladder tumor were evaluated and compared with intact tissues from tumor margins and normal bladders.