Enhanced degradation of Ciprofloxacin (CIP) antibiotic and methylene blue (MB) dye using ZnO/GO nanocomposites under solar irradiation.

Modifying ZnO nanorods with graphene oxide (GO) is crucial for enhancing photocatalytic degradation by boosting the concentration of reactive oxygen species (ROS) in the reaction medium. In this study, we present a straightforward chemical synthesis of ZnO nanorods embedded on GO, forming a novel nanocomposite, GOZ. This composite serves as an efficient photocatalyst for the sunlight-driven degradation of methylene blue (MB) and ciprofloxacin (CIP).

Utility of Bedside Ultrasound Measurement of Optic Nerve Sheath Diameter as a Screening Tool for raised Intracranial Pressure in Neurocritical Care Prospective Observational Study.

Intracranial pressure (ICP) needs to be monitored in neurocritical patients. There is a need for portable bedside optic nerve ultrasound (ONUS) for early diagnosis to initiate the measures to reduce ICP Objective: To find the utility of bedside ONUS to diagnose raised ICP in neurocritical care. Materials and methods: After approval from the ethical committee, a prospective observational study was conducted.

Incidence, Subtypes, Risk factors, and Outcome of Delirium: A Prospective Observational Study from Indian Intensive Care Unit.

Background: Delirium is a common, under-recognized, and often fatal condition in critically ill patients, characterized by acute disorder of attention and cognition. The global prevalence varies with a negative impact on outcomes. A paucity of Indian studies exists that have systematically assessed delirium.

Synthesis and antibacterial activity of nanoenhanced conjugate of Ag-doped ZnO nanorods with graphene oxide.

In this paper, we report a successful synthesis of ZnO nanorods using the microwave-assisted technique, solid-state reaction method was utilized for the preparation of ZnAgO (x = 0.05, 0.1), Hummer's modified method for graphene oxide (GO) along with the sonication method to prepare GO-based Ag-doped ZnO (ZnAgO/GO: x  = 0.

Probing the interaction of zinc oxide nanorods with human serum albumin: A spectroscopic approach.

Bio-functionalized metal oxide nanoparticles (NPs) have been taken great importance in biomedical fields. The use of nanoparticles as delivery agents of therapeutic molecules led the researchers to emphasize the potential impact of these NPs on bio-macromolecules as protein-nanoparticle complexes, which also extended their importance as vehicles in targeted drug delivery systems due to increased ease of administration, firmness, reduced toxic side effects, and half-life of drugs. Since human serum albumin is the blood protein responsible for transporting materials in the blood system, the interaction of these particles with HSA is essential to be understood before considering the nanoparticles for any individual biomedical application.

Nitrogenous Fertilizer Coated With Zinc Improves the Productivity and Grain Quality of Rice Grown Under Anaerobic Conditions.

An ample quantity of water and sufficient nutrients are required for economical rice production to meet the challenges of ever-increasing food demand. Currently, slow-release nitrogenous fertilizers for efficient inputs utilization and maximum economic yield of field crops are in the limelight for researchers and farmers. In this study, we evaluated the comparative efficacy of conventional urea and coated urea (zinc and neem) on rice grown under aerobic and anaerobic regimes in greenhouse conditions.

Synthesis of gallotannin capped iron oxide nanoparticles and their broad spectrum biological applications.

Green synthesized nanoparticles (NPs) have attracted enormous attention for their clinical and non-clinical applications. A natural polyphenol, gallo-tannin (GT) was used to reduce and cap the FeO-NPs. GT-FeO-NPs were synthesized following co-precipitation of FeCl and FeSO·7HO with GT.

Despite Major Therapeutic Advances, Vena Caval Trauma Remains Associated with Significant Morbidity and Mortality.

Background: Penetrating inferior vena caval injuries remain a challenging operative entity. This study reviews our local experience with the injury over a nine-year period and attempts to contextualize it within the published literature that emanates from South Africa on the topic.

Methods: A single-centre retrospective review of prospectively collected data was performed of all patients who underwent a laparotomy for a penetrating IVC injury.

Case Report: Atypical Presentation of Neuroretinitis in a Middle-aged Woman with Pre-existing Maculopathy.

Significance: Neuroretinitis classically presents with sudden vision loss, disc edema, and macular star formation. However, the classical triad may not always be seen, especially in the case of a pre-existing macular disorder. A thorough clinical examination may still clinch the appropriate diagnosis and prevent unwarranted treatment.

Timing of Invasive Mechanical Ventilation and Mortality among Patients with Severe COVID-19-associated Acute Respiratory Distress Syndrome.

Background: Severe acute respiratory distress syndrome associated with coronavirus disease-2019 (COVID-19) (CARDS) pneumonitis presents a clinical challenge as regards to the timing of intubation and ambiguity of outcome. There is a lack of clear consensus on when to switch patients from trials of noninvasive therapies to invasive mechanical ventilation. We investigated the effect of the timing of intubation from the time of admission on the clinical outcome of CARDS.

Mechanistic insight into the binding of graphene oxide with human serum albumin: Multispectroscopic and molecular docking approach.

Increasing manufacturing and use of nanoparticles in industrial and biomedical applications creates the necessity to understand the impact of the interaction of nanoparticles with biomacromolecules. In the present study, graphene oxide nanosheets (GONS) were synthesized using modified Hummer's method and further characterized employing X-ray diffraction (XRD), UV, FTIR, and Raman spectroscopy. After characterization, the interaction of GONS with human serum albumin (HSA) was investigated to delineate the binding mechanism employing different kinds of spectroscopic techniques.

Giant Extra-Articular Synovial Chondromatosis of the Ankle Joint - A Rare Case Report.

Introduction: Synovial chondromatosis (SC) commonly involves large joints such as the knee and hip with smaller joints being less frequently involved. Extra-articular involvement is very rare, and here, we are presenting the first case of giant extra-articular SC originating from the ankle joint.

Case Report: A 42-year-old male presented to the outpatient department with painless swelling over the lateral malleolus for 2 years.

Do the existing systemic diseases overstate anaesthetic intervention during cataract surgery under local anaesthesia? An observational study to correlate the association.

Context: The objective was to study the extent of anaesthetic intervention and its association with systemic comorbidities. The secondary objectives were to estimate the prevalence of systemic comorbidities in age-related cataracts.

Aims: To determine the prevalence of systemic comorbidities in cataract surgery patients and association with anaesthesiologists' intervention.

High insertion of cystic duct at the gallbladder fundus: An undescribed anomaly!

The anatomy of the biliary tree is complex, and its variations of both intra- and extra-hepatic bile ducts can be found in approximately 30% of the general population. These variations are not picked up on routine pre-operative investigations of patients planned for a laparoscopic cholecystectomy (LC) and often present as an unusual 'surprise' and a challenge that can make dissection in the Calot's triangle difficult leading to iatrogenic injury. We present a case of a 53-year-old female with an undescribed anomaly encountered during an LC.

Success rate of probing for congenital nasolacrimal duct obstruction at various ages.

Purpose: To determine the success rate of probing for congenital nasolacrimal duct obstruction (CNLDO) in various age groups.

Methods: One hundred children (118 eyes) aged 4 to 48 months diagnosed with CNLDO were included and divided into 6 groups; group 1: infants 4-6 months of age, group 2: infants from 7 to 12 months, group 3: toddlers 13-18 months of age, group 4: older toddlers 19-24 months old, group 5: children from 25 to 36 months, and group 6: children 37-48 months of age. Probing was performed under general anesthesia in all subjects.

Partially folded intermediate state of concanavalin A retains its carbohydrate specificity.

A systematic investigation of the effect of polyethylene glycol (PEG) 200 and 400 on the solution conformation of concanavalin A (con A) was made using circular dichroism (CD), tryptophan fluorescence, 1-anilino-8-naphthalenesulfonic acid (ANS) binding, and size-exclusion chromatography. Far-UV CD spectra of con A at 30%(v/v) PEGs show the retention of ordered secondary structure as compared to 70%(v/v) PEGs. Near-UV CD spectra showed the retention of native-like spectral features in the presence of 30%(v/v) PEGs.