Publications by authors named "Afroditi Kokkosi"
Article Synopsis
- Organometallic complexes of ruthenium, specifically those featuring bidentate polypyridyl ligands and -cymene, are being investigated as potential cancer treatments, focusing on their cytotoxic properties.
- A series of new ruthenium(II)-arene complexes with modified quinoline ligands were synthesized to explore their effects on the ruthenium -cymene complexes' activity.
- Initial in vitro tests on human kidney (HEK293T) and cervical cancer (HeLa) cells using the MTT assay revealed poor anticancer activity for the new complexes, with the ligand precursor pqhyme showing significantly higher cytotoxicity compared to the traditional chemotherapy drug cisplatin.
