Single dose oral pharmacokinetic profile rubraxanthone in mice.

Rubraxanthone is a main active constituent of kandis ( Roxb), has showed many biological activity including antimicrobial, anti hypercholesterolemic, antiplatelet, antioxidant, cytotoxic, and anti-inflammatory properties. To the best of our knowledge, no reports on the pharmacokinetics (PK) of this rubraxanthone have been published. The PK of rubraxanthone in mice was examined after a single oral dose of 700 mg/kg rubraxanthone suspension in virgin coconut oil.

Comparative Study of Phytochemical, Antioxidant, and Cytotoxic Activities and Phenolic Content of (Burm. f. Alston f.) Extracts Growing in West Sumatera Indonesia.

, consisting of various fruit colors, is one of the plants that have been used as traditional medicine. This study aims to evaluate and compare phytochemical, antioxidant, and cytotoxic activities and total phenolic content of leaves and stem bark extracts of with pink and red fruits, in order to identify the best extract that can be used as a natural antioxidant. Phytochemical constituents were evaluated qualitatively using chemicals, while cytotoxic activities were identified using the brine shrimp lethality test.

Antioxidant activities, cytotoxic properties and total phenolic content of Syzygium malaccense (L.) Merr. & L.M. Perry leaves extracts: A West Sumatera Indonesian plant.

The purpose of this study was to determine the antioxidant activities and cytotoxic properties of the various extracts of Syzygium malaccense leaves and its correlation with total phenolic content. To determine the antioxidant properties 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydrogen peroxide methods have been used while to determine cytotoxic properties brine shrimp lethality test method has been used. Furthermore, to determine total phenolic content the Folin-Ciocalteu method has been carried out.