Enhancing cancer care through addressing a neglected pillar: a narrative review on quality of life in Pakistani patients.

The current narrative review was planned to evaluate the quality of life of Pakistani cancer patients. Using relevant questionnaires and comparing global data over the last 2 decades, the review planned to explore artificial intelligence's role in cancer care, and to develop strategies for better outcomes. The review yielded poor results and exposed huge and neglected gaps in the overall approach towards the management of cancer patients based on different tumour types and categories.

Analytical approaches and advancement in the analysis of natural and synthetic fiber: A comprehensive review.

Background: Accurately determining fiber composition is essential for optimizing material properties across diverse applications in textiles, composites, packaging, and other bio-based materials. Fiber performance in textiles, composites, and bio-based materials depends upon their intricate composition. This review explores advanced analytical techniques for the comprehensive characterization of natural (cellulose-hemicellulose-lignin) and synthetic (polymeric) fibers.

Determination of Electrolytes and Trace Elements in Biological Samples from Patients with Altered Semen Parameters: a Correlational Analysis.

The effects of important nutrients such as calcium (Ca), copper (Cu), iron (Fe), magnesium (Mg), selenium (Se), and zinc (Zn) have been investigated in relation to male fertility due to their roles in proper spermatogenesis, sperm maturation, motility, and optimal sperm function. An imbalance between these elements has been associated with several pathologic conditions and male reproductive issues. The purpose of this study was to determine the essential trace and electrolytes elements, such as Ca, Cu, Fe, Mg, Se, and Zn, in human biological samples (blood, serum, and semen) from patients with male infertility.

Analyzing Data Modalities for Cattle Weight Estimation Using Deep Learning Models.

We investigate the impact of different data modalities for cattle weight estimation. For this purpose, we collect and present our own cattle dataset representing the data modalities: RGB, depth, combined RGB and depth, segmentation, and combined segmentation and depth information. We explore a recent vision-transformer-based zero-shot model proposed by Meta AI Research for producing the segmentation data modality and for extracting the cattle-only region from the images.

Evaluate the aluminum concentrations in whey milk samples of cows from different areas using deep eutectic solvent-based ultrasound-assisted dispersive liquid-liquid microextraction method.

This study investigates the contamination of cow milk with aluminum (Al) and its potential health implications, particularly for children. Cow milk samples were collected from both nonexposed and exposed areas in Sindh, based on the source of livestock drinking water (fresh canals and groundwater). An environmental friendly deep eutectic solvent (DES) was used with ultrasonic-assisted dispersive liquid-liquid microextraction (UDLLμE) to enrich trace amounts of Al in whey milk and water samples.

Evaluate the Work-Related Exposure of Vanadium on Scalp Hair Samples of Outdoor and Administrative Workers of Oil Drilling Field: Related Health Risks.

Petrochemical facilities, including oil well drilling, are discharging resources of extensive noxious waste into the environment. The workers in different sections might be exposed to vanadium (V) through different routes (groundwater and soil), which is linked with extensive physiological disorders, hypertension, respiratory disorders, anemia, skin, and gastrointestinal disorders. This study determined the contents of V in a biological sample (scalp hair) of workers of different categories (outdoor and office workers) in an oil drilling field in Sindh, Pakistan.

Bioremediation of Neonicotinoid Pesticide, Imidacloprid, Mediated by .

Imidacloprid, a toxic pesticide of the chloronicotinyl category, is employed extensively in agricultural fields, and its exposure causes serious health issues. Biodegradation is considered to be a green and economical approach to remediate pesticides. Herein, imidacloprid degradation efficiency of sp.

The green synthesis of magnesium oxide nanocomposite-based solid phase for the extraction of arsenic, cadmium, and lead from drinking water.

Solid-phase extraction (SPE) has attracted the attention of scientists because it can increase the selectivity and sensitivity measurements of analytes. Therefore, this study is designed to synthesise magnesium oxide nanoparticles (D-MgO-NPs) by an eco-friendly method using biogenic sources followed by fabricating its chitosan-based polymeric composite (D-MgO-NC) for the SPE of heavy metals (HMs), , arsenic (As), cadmium (Cd), and lead (Pb) from drinking water. Various analytical techniques were used for the surface characterization of D-MgO-NPs and D-MgO-NC.

Mitigating marine hazardous contaminants: A sustainable management perspective.

Marine hazardous contaminants, such as cadmium (Cd) and lead (Pb), pose significant risks to both human health and aquatic organisms. Traditional methods may not remove contaminants to safe levels, leading to the release of hazardous materials into marine environments. This research proposes polymeric membrane bioreactors as a potential solution to this problem.

The importance of monitoring endocrine-disrupting chemicals and essential elements in biological samples of fertilizer industry workers.

Exposure to endocrine-disrupting chemicals (EDCs) can lead to adverse health effects, including immune and endocrine system disruption, respiratory problems, metabolic issues, diabetes, obesity, cardiovascular problems, growth impairment, neurological and learning disabilities, and cancer. Fertilizers, which contain varying levels of heavy metals, are known to pose a significant risk to human health, especially for those residing or working near fertilizer industries. This study aimed to investigate the levels of toxic elements in biological samples of individuals working in a fertilizer industry's quality control and production units and those residing within 100-500 m of the industry.

Environmental impact of endocrine-disrupting chemicals and heavy metals in biological samples of petrochemical industry workers with perspective management.

Exposure to endocrine disrupting chemicals (EDCs) or heavy metals are synthetic compounds that can lead to negative effect on health, including immune and endocrine system disruption, respiratory problems, metabolic issues, diabetes, obesity, cardiovascular problems, growth impairment, neurological and learning disabilities, and cancer. Petrochemical industry drilling wastes, which contain varying levels of EDCs, are known to pose a significant risk to human health. This study aimed to investigate the levels of toxic elements in biological samples of individuals working in the petrochemical drilling sites.

Correlation of endocrine disrupting chemicals with essential elements in biological samples of children (1-5 years) with different infectious diseases and impact on sustainable outdoor activities.

Endocrine disrupting chemicals (EDCs) have been extensively explored due to their harmful effects on individual health and the environment by interfering with hormone activity and disrupting the endocrine system. However, their relationship with essential trace elements remains uncertain. This research aimed to investigate the possible correlation between essential trace elements and toxic metals, including cadmium (Cd), and lead (Pb) in children aged 1-5 years with various infectious diseases, including gastrointestinal disorders, typhoid fever, and pneumonia.

Effect Of Lead On The Skin And Health Of Female Dermatitis Patients Through Cosmetics.

Background: Cosmetics have been a part of routine body care not only for the upper classes but also for the middle and lower classes since the dawn of civilization. Cosmetic formulations are in more demand as the public's interest in skin whitening grows. The contamination of cosmetics with heavy metals is a major concern as they containing heavy metals and pose a major risk to human health.

Determination of toxic elemental levels in whey milk of different cattle and human using an innovative digestion method: risk assessment for children < 6.0 months to 5 years.

In present study, the toxic elements, arsenic (As), cadmium (Cd), and lead (Pb), were determined in whey milk samples obtained from various cattle (cow, goat, buffalo, sheep, camel) and human subjects of different areas of Sindh, Pakistan, based on consuming drinking water (exposed area) and surface water (control/non-exposed area). The whey milk was separated from casein by lowering the pH, and heating in an ultrasonic bath at 60 °C for 5 min and centrifuged. The whey milk samples were treated with deep eutectic solvent, prepared from choline chloride-oxalic acid (ChCl-Ox) at different mole ratio.

Chemical association of copper and selenium in coals of Sindh by time saving single step strategy and their impact on groundwater.

The aim of the present study is to estimate the different chemical fractionations of copper (Cu) and selenium (Se) in coal samples of different coal mining areas. The Cu and Se bound to various chemical fractions of coal collected from two mining fields of Sindh, Pakistan, have been determined by BCR sequential extraction scheme (BCR-SES). The long duration of the BCR sequential scheme (51 h) was reduced by a time-saving shaking device (ultrasonic bath) termed as ultrasonic-assisted extraction (USE) depending on the same operating conditions and extracting solutions used for BCR sequential extraction scheme.

Biosynthesis and Analytical Characterization of Iron Oxide Nanobiocomposite for In-Depth Adsorption Strategy for the Removal of Toxic Metals from Drinking Water.

The biosynthesis of the iron oxide nanoparticles was done using leaf extract, followed by the fabrication of iron oxide nanobiocomposites (I-FeO-NBC) using chitosan biopolymer. Furthermore, the synthesized I-FeO-NPs and I-FeO-NBC were characterized, and I-FeO-NBC was applied to remove toxic metals (TMs: Cd, Ni, and Pb) from water. The characterization study confirmed that the nanostructure, porous, rough, crystalline structure, and different functional groups of chitosan and I-FeO-NPs in I-FeO-NBCs showed their feasibility for the application as excellent adsorbents for quantitative removal of TMs.

Risk Assessment of Macronutrients and Minerals by Processed, Street, and Restaurant Traditional Pakistani Foods: a Case Study.

The current work is aimed to assess the impact of macronutrient and mineral contents in food products of packaged food, restaurant food, and street food in Hyderabad. The estimated daily intake of macronutrients and minerals, followed by the toxic risk assessment of microminerals by consuming studied food dishes, was also conducted. The collected products were freeze-dried and standard procedures for measuring macronutrients were followed.

Synthesis and Investigation of the Analgesic Potential of Enantiomerically Pure Schiff Bases: A Mechanistic Approach.

Schiff bases are a class of organic compounds with azomethine moiety, exhibiting a wide range of biological potentials. In this research, six chiral Schiff bases, three ‘S’ series (H1−H3) and three ‘R’ series (H4−H6), were synthesized. The reaction was neat, which means without a solvent, and occurred at room temperature with a high product yield.

Selenium and mercury concentrations in biological samples from patients with COVID-19.

Background: Coronavirus disease 2019 (COVID-19) is a systemic disease affecting multiple organs. Furthermore, viral infection depletes several trace elements and promotes complex biochemical reactions in the body. Smoking has been linked to the incidence of COVID-19 and associated mortality, and it may impact clinical effects, viral and bacterial conversion, and treatment outcomes.

An environmental field assessment of soil quality and phytoremediation of toxic metals from saline soil by selected halophytes.

The current study has aims to investigate the soil quality and phytoextraction of cadmium (Cd), chromium (Cr), and lead (Pb) from saline soils using (camelthorn), (saltcedar), (mustard bush), and (bush seep weed). The saline bulk soil, rhizospheric soil, and different parts of selected plants were oxidized using the acid mixture and determined Cd, Cr, and Pb by atomic absorption spectrometry. The bio-concentration factor (BCF) and translocation factor (T) of also examined.

Determining the level of essential elements in patients with Ewing Sarcoma: A correlation.

Background: Metal ion aberrant metabolism is essential for health and disease, and its research has sparked a lot of interest. This study aims to compare the critical mineral resources-magnesium (Mg), sodium (Na), calcium (Ca) and potassium (K)-in biological materials (scalp hair, blood, and serum) of 87 Ewing Sarcoma (ES) hypertensive men and women, age range 31-60 years, in an urban area, with 62 nonhypertensive subjects from the same age range and living area.

Methods: An atomic-absorption spectrophotometer was used after microwave-induced acid digestion to determine elemental concentrations.