Synopsis of recent research by authors named "Afreen Inam"
- Afreen Inam's research primarily focuses on the synthesis and biological evaluation of novel compounds aimed at combatting protozoal infections and cancer, particularly targeting Entamoeba histolytica and various cancer-related pathways such as MARK4 and p38MAPK.
- Her notable contributions include the development of metronidazole-based thiazolidinone analogs, which show promise as antiamoebic agents with reduced toxicity, along with the discovery of hydrazone derivatives that act as MARK4 inhibitors, suggesting potential applications in cancer therapy.
- In addition to targeting specific diseases, her studies demonstrate a strong emphasis on designing multifunctional agents capable of inhibiting key biochemical pathways and offering improved therapeutic profiles, as evidenced by her work on hybrid antiprotozoal agents and sulfonamide derivatives.