Neuroprotective Effect of Maresin-1 in Rotenone-Induced Parkinson's Disease in Rats: The Putative Role of the JAK/STAT Pathway.

Exposure to rotenone results in similar pathophysiological features as Parkinson's disease. Inflammation and oxidative stress are essential to PD pathogenesis. Maresin-1 has potent anti-inflammatory properties and promotes the regression of inflammation function.

Iron Deficiency Anaemia in Pregnancy: A Narrative Review from a Clinical Perspective.

Anaemia in pregnancy is a global problem of significance in all settings. The most common cause is iron deficiency. Large numbers of women are affected, ranging up to 25-30% antenatally and 20-40% postnatally.

Low versus standard dose intravenous alteplase in the treatment of acute ischemic stroke in Egyptian patients.

Objectives: To assess low dose altepase outcome and safety in comparison with a standard-dose regimen for acute ischemic stroke treatment in Egyptian patients.

Materials: An observational prospective cohort non-randomized single blinded study was carried out during the period from November 2017 to December 2018. Eighty Egyptian acute ischemic stroke patients, all eligible for intravenous alteplase, were subdivided into 2 groups (40 patients in each group).

Blood loss from transverse versus longitudinal uterine incision in abdominal myomectomy: a randomized controlled trial.

Background: It is unclear whether transverse uterine incision is non-inferior to longitudinal incision during myomectomy with regard to bleeding. Our aim was to compare between transverse and longitudinal uterine incisions in myomectomy.

Methods: A parallel randomized controlled single-blinded study in a university affiliated hospital, in the period between January 2017 and April 2018, in which 52 women candidates for abdominal myomectomy were randomized into transverse uterine incision or longitudinal uterine incision groups (26 in each group).

Correction to: Features of intracranial hemorrhage in cerebral venous thrombosis.

The original version of this article unfortunately contained mistakes. The correct information is given below.

Features of intracranial hemorrhage in cerebral venous thrombosis.

Background: Cerebral venous thrombosis (CVT) is associated with intracranial hemorrhage.

Aim: To identify clinical and imaging features of CVT-associated intracranial hemorrhage. We hypothesized that higher clot burden would be associated with a higher risk of intracranial hemorrhage.

Improving classical scoring functions using random forest: The non-additivity of free energy terms' contributions in binding.

Despite recent efforts to improve the scoring performance of scoring functions, accurately predicting the binding affinity is still a challenging task. Therefore, different approaches were tried to improve the prediction performance of four scoring functions (x-score, vina, autodock, and rf-score) by substituting the linear regression model of classical scoring function by random forest to examine the performance improvement if an additive functional form is not imposed, and by combining different scoring functions into hybrid ones. The datasets were derived from the PDBbind-CN database version 2016.

Management of endometrial polyps in subfertile women: a systematic review.

The aim of this systematic review is to evaluate the evidence for the impact of polypectomy on fecundity, implantation and live birth rates in women who are trying to conceive spontaneously or by assisted conception. A literature search was performed to identify all controlled studies that compared the effects of polypectomy or conservative management of the polyp on pregnancy outcome. Among the three studies that met the inclusion criteria, only one was a randomized controlled trial, which reported a significantly higher pregnancy rates after polypectomy in women undergoing intrauterine insemination.

[Wear measurements of hip prostheses with UHMW polyethylene (RCH-1000) socket and chromium plated protasul-10 head (author's transl)].

An estimation of wear was carried out on 100 of 340 UHMW polyethylene sockets (RCH 1000) that were implanted with Protasul-10 prostheses furnished with a chromium plated head. This was effected by measuring the position of the head relative to the socket as seen on radiographs during a follow-up period of 4 years. The method employed was verified in 3 cases (in which the socket had been removed) by measurements on silastic casts of the bearing surface.