[The main aspects of the multidisciplinary dispensary dental care to elderly and senile population].

In the article presents the characteristics of the organization of dispensary work with patients older than 60 years. The main directions and objectives dispensary. The features of clinical supervision of dental patients belonging to the category of persons decreed by the elderly, senile age from the perspective of interaction professionals in a multidisciplinary clinic.

Mechanisms of antioxidant effect of natural sesquiterpene lactone and alkaloid derivatives.

We performed screening of potential antioxidants among natural lactone and alkaloid derivatives and characterized their antioxidant effects. The substances exhibiting antioxidant and metal-chelating potential, in particular, tryptamine derivatives, are promising neuroprotector agents.

[Structural mechanisms and mathematical modeling of the bone tissue damage caused by hyper-speed impact].

Method of computer modeling of behavior of cylindrical and lamellar bones under the hypervelocity impact is suggested. This method allows in the frame of mechanics of continuous medium to calculate the stress strain behavior and damage in bone tissues under the shock wave impact. The processes of shock correlation of steel fragments of different shape with diaphysis of cylindrical bones and flat bone of calvaria under the impact 500 m/s are studied.

[Program of diagnosis and care of patients with " cardialgia " in general practice].

A team of primary medical aid examined patients with diagnosis " cardialgia " in a district served by a general practitioner. Basing on objective physical diagnosis and parameters of psychological and social status of patients obtained by this team clinical recommendations on organization of diagnostic process and intervention programs were prepared.

[The pathogenetic role of the infection component in children with lymphadenopathy under modern conditions].

Apart from lymphadenopathy types observed in well-known diseases (oncology and hematology pathologies, systemic lesions of connective tissues, tuberculosis, brucellosis, infection mononucleosis, toxoplasmosis, AIDS and other specific processes), there is an extensive group of lymphadenopathy (up to 70% of all disease cases), whose cause cannot be diagnosed by using the routine examination schemes. This was reflected in the diagnosis of "lymphadenopathy of unverified etiology" according to the MKB-1 now in force. Investigations of the role (in etiopathogenesis) of unverified lymphadenopathy types as observed in children with the infection component as well as optimization of their diagnosis and treatment schemes are elucidated in the paper.

[The protective effect of trimetazidine on the myocardium against reperfusion injury during thrombolytic therapy of acute infarction].

Investigation of the protective action of the antiischemic drug trimetazidine (60 mg/kg) used during thrombolytic treatment of acute infarction showed that the drug effectively inhibits lipid peroxidation and reduces the degree of the reperfusive damage of myocardium, as determined from ECG (QRS index calculation) or from data on the blood creatinin phosphokinase level.

[The effect of immunomodulators on the development of antibodies to the diphtheria antigen in mice vaccinated with the DTP adsorbed vaccine].

An animal model for the study of the influence of immunomodulators on the development and preservation of postvaccinal antidiphtheria immunity was experimentally selected and the corresponding study was carried out. In this work the following immunomodulators were used: dibasol, prodigiosan, splenin, thymalin, reaferon, tactivin, methyluracyl. The study revealed that by day 120 of observation all immunomodulators stimulated the production of antibodies in higher titers than adsorbed DPT vaccine, introduced without immunomodulators.

[The effect of recombinant tumor necrosis factor on antibody formation in mice immunized with a preparation of the outer membranes from Francisella tularensis].

The influence of exogenic human recombinant tumor necrosis factor (TNF-alpha) on antibody production in mice immunized with the preparation of F.tularensis outer membranes (OM) was studied. TNF-alpha was injected into mice in doses of 0.

[The level of postvaccinal immunity to diphtheria, tetanus and poliomyelitis in relation to the number of inoculations].

The work was aimed at the comparative study of the intensity of immunity to diphtheria, tetanus and poliomyelitis, depending on the number of injections of adsorbed diphtheria-pertussis-tetanus (DPT) vaccine and poliomyelitis vaccine, for the purpose of finding out the possibility of reducing the antigenic load given to children without diminishing the intensity of immunity. To determine the level of immunity to diphtheria and tetanus, 1900 children under school age were serologically studied by the micromethod in the passive hemagglutination test. The intensity of immunity to poliomyelitis virus was studied in 333 children by means of the neutralization test.

[Effect of dekaris on the immunity indices in pneumonia and diabetes mellitus].

Effect of decaris on dynamics of cellular and humoral immunity was studied in 55 patients with acute and chronic pneumonia and 40 patients with diabetes mellitus. Differences in dynamics of immune parameters in diabetes mellitus and pneumonias in response to decaris treatment were found that could be related to various mechanisms of immune disturbances in these diseases.

[Characteristics of Proteus, Klebsiella, Enterobacter and Citrobacter strains isolated in urological infections].

The comparative study of more than 300 Proteus, Klebsiella, Enterobacter and Citrobacter strains isolated from patients with urological infections and parenteral infections of other localization, as well as from the feces of healthy persons has been carried out. The strains causing inflammatory processes in the urinary tract have been shown to possess no strict specificity. The ability of opportunistic enterobacteria to cause urinary tract lesions is their polydeterminant property ensured by the combination of different factors.

[Heterogeneity of the fatty acid composition of bacteria in the genera Klebsiella, Enterobacter, Hafnia and Serratia].

The analysis of the chromatograms of methyl esters of fatty acids in bacterial strains of the tribe Klebsielleae showed the heterogeneity of the fatty acid composition of bacteria belonging to the genera Klebsiella, Enterobacter, Hafnia and Serratia. The bacteria of this tribe could be subdivided into 5 provisory groups in accordance with the composition and profile of their fatty acids. Group I comprised K.