Publications by authors named "Afaf Helmy"

Article Synopsis
  • TSLP, a cytokine associated with allergic reactions, may work with CD40L to increase IL-23 production in psoriasis, a skin condition caused by an inappropriate immune response.
  • The study involved 53 psoriasis patients, classified by severity based on the PASI score, and compared their serum TSLP levels to a control group of 53 healthy individuals.
  • Results indicated significantly higher TSLP levels in psoriasis patients compared to controls, with levels correlating positively with disease severity, suggesting TSLP could be a potential marker for psoriasis severity.
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Trichoscopy corresponds to the scalp, and hair dermoscopy has been increasingly used as an aid in the diagnosis, follow-up, and prognosis of hair disorders. Trichoscopy represents a valuable link between clinical and histological diagnosis. Tinea capitis (TC) and alopecia areata (AA) are considered the most common causes of hairless patches of the scalp in pediatrics.

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Background: Platelet-rich plasma (PRP) is an autologous preparation of platelets in concentrated plasma that may be beneficial in the treatment of atrophic acne scars by promoting collagen deposition. Skin needling is a technique that uses a sterile dermaroller to puncture the skin and release growth factors. The combination of skin needling and PRP could enhance the efficacy of both modalities.

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Background: Despite their benign nature, keloids are usually associated with considerable cosmetic effects and may lead to functional problems. Recently, it has been reported that vascular endothelial growth factor (VEGF), a potent angiogenic factor, is overexpressed in keloid tissue and may have a potential role in its evolution.

Methods: Twenty patients with keloids were included in this study and classified into two groups according to the treatment received: intralesional triamcinolone acetonide 20 mg/mL (group 1) and cryotherapy spray technique (group 2).

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