Publications by authors named "Aerin Thomson"
Article Synopsis
- Inflammation is linked to frailty, but the impact of anti-inflammatory medications like canakinumab on frailty risk remains uncertain due to limited trial evidence.
- The CANTOS trial involved over 10,000 post-heart attack patients, assessing if canakinumab, which inhibits IL-1β, could lower frailty incidence over 5 years through a detailed Frailty Index.
- Results showed no significant difference in frailty incidence between participants receiving canakinumab and those on placebo, indicating that more research is required to understand the potential benefits of anti-inflammatory treatments for preventing frailty in older adults.
