Publications by authors named "Aedrian A Abrilla"
Objective: This study aimed to identify the effects of COVID-19 pandemic on radiation treatment delays, interruptions, and cancer outcomes if any, in a Philippine tertiary hospital.
Methods: A retrospective observational cohort study was conducted among patients living with cancer who were referred for radiation therapy from March to July 2020. Data on treatment delays, treatment interruptions, and average treatment times were collected and analyzed.
Article Synopsis
- Pityriasis versicolor is a common fungal skin infection, typically treated with keratolytic agents, which are cheap and available over-the-counter, while conventional antifungals are pricier and require prescriptions.
- The goal of this study was to systematically review and compare the safety and effectiveness of these antifungal treatments against keratolytic agents for managing pityriasis versicolor.
- The review included data from 8 randomized controlled trials with 617 participants, using statistical analysis to evaluate the outcomes, although publication bias could not be assessed due to the limited number of studies.
Saliva has been demonstrated as feasible alternative to naso-oropharyngeal swab (NOS) for SARS-CoV-2 detection through reverse transcription quantitative/real-time polymerase chain reaction (RT-qPCR). This study compared the diagnostic agreement of conventional NOS, saliva with RNA extraction (SE) and saliva without RNA extraction (SalivaDirect) processing for RT-qPCR in identifying SARS-CoV-2. All techniques were also compared, as separate index tests, to a composite reference standard (CRS) where positive and negative results were defined as SARS-CoV-2 detection in either one or no sample, respectively.
View Article and Find Full Text PDFAim: To compare the efficacy and tolerability of metformin extended-release (MXR) and the conventional metformin immediate-release (MIR) formulations in adults with type 2 diabetes mellitus (T2DM) METHODS: PubMed, the Cochrane Library, ClinicalTrials.gov and other sources were searched until 19 March 2021 for randomized controlled trials (RCTs) that compared equal daily doses of MXR and MIR in adults with T2DM. Random-effects model meta-analysis was performed to obtain pooled mean difference (MD) of change from baseline for continuous outcomes and risk ratio (RR) for dichotomous outcomes.
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