Publications by authors named "Adulaziz A Alsaif"
Article Synopsis
- - This study investigates the relationship between certain gene variants (SNPs) in p21 and bcl2 and the risk of breast cancer in Saudi women, as previous studies on this population haven't been conclusive.
- - The research found that while the p21 variant (rs733590) was not linked to breast cancer, the T/C reverse mutation might be associated with the disease, and bcl2 genotypes showed a marginal connection with risk.
- - Specifically, a higher frequency of the G allele in bcl2 was noted in breast cancer patients, and the AA genotype significantly increased the risk compared to AG+GG genotypes, suggesting these genetic factors could elevate breast cancer susceptibility in this group.
Breast cancer is the most common oncological disease in women worldwide. Genetic predisposition to breast cancer can be associated with single-nucleotide polymorphisms (SNPs), which are observed in many women. Such gene polymorphisms, in combination with nutritional and environmental factors, can affect breast cancer development.
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