Publications by authors named "Adrijana Kekic"
Article Synopsis
- Coccidioidomycosis can lead to serious meningitis, which needs long-term treatment.
- A study examined how pharmacogenomic testing (analyzing genetic variations) could impact treatment outcomes for patients with coccidioidal meningitis.
- Out of 13 patients tested, 11 had genetic variants that influenced antifungal effectiveness, resulting in immediate treatment adjustments and showing that such testing can prevent ineffective or harmful treatments.
Background: There is a paucity of evidence to inform the value of pharmacogenomic (PGx) results in patients after kidney transplant and how these results differ between Indigenous Americans and Whites. This study aims to identify the frequency of recommended medication changes based on PGx results and compare the pharmacogenomic (PGx) results and patients' perceptions of the findings between a cohort of Indigenous American and White kidney transplant recipients.
Methods: Thirty-one Indigenous Americans and fifty White kidney transplant recipients were studied prospectively.
Background: Pharmacogenomics is an emerging and affordable tool that may improve postoperative pain control. One challenge to successful pain control is the large interindividual variability among analgesics in their efficacy and adverse drug events. Whether preoperative pharmacogenomic testing is worthwhile for patients undergoing TKA is unclear.
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- The Mayo-Baylor RIGHT 10K Study focused on using pharmacogenomics to improve drug prescriptions based on genetic information in a large population.
- Researchers sequenced the DNA of over 10,000 participants to identify genetic variations affecting drug responses, and integrated these findings into electronic health records.
- Results showed that 79% of participants had actionable genetic variants affecting their medication, highlighting the need for a proactive approach to personalized medicine in clinical care.
Clinical Review of the Pharmacogenomics of Direct Oral Anticoagulants.
Cardiovasc Drugs Ther
February 2018
Purpose: There is growing interest in the use of pharmacogenomics to optimize the safety and efficacy of anticoagulation therapy. While the pharmacogenomics of warfarin have been well-studied, the pharmacogenomics of direct oral anticoagulants (DOACs) continue to be a fledgling, but growing, field of interest. We present a pertinent clinical review of the present state of research on the pharmacogenomics of DOACs.
View Article and Find Full Text PDFA systematic review was conducted to examine the association between fish oil supplementation and the development of asthma exacerbations. Comprehensive literature reviews of recent fish oil studies were performed to evaluate alterations in asthma surrogate markers. Additionally, the relative compositions of the fish oils used in each study were analyzed.
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