Reflectance confocal microscopy for the evaluation of acute epidermal wound healing.

The dynamic process of wound healing is routinely evaluated by clinical or histological evaluation. Recently, a number of non-invasive imaging techniques have been evaluated for their clinical applicability in dermatology. Among them, reflectance confocal microscopy (RCM) represents a non-invasive imaging technique that allows the in vivo characterization of the skin at near-histological resolution.

Modes of action of diclofenac 3%/hyaluronic acid 2.5% in the treatment of actinic keratosis.

Background: The efficacy of topically applied diclofenac 3 % in combination with hyaluronic acid 2.5 % in the treatment of actinic keratoses (AKs) has been demonstrated in several clinical studies, but the exact mode of action is still unclear. This study evaluates the potential molecular and cellular main modes of action of topically applied diclofenac in the treatment of AKs.

Clinical applicability of in vivo reflectance confocal microscopy for the diagnosis of actinic keratoses.

Background: In vivo reflectance confocal microscopy (RCM) has been used for evaluation of the morphologic features of nonmelanoma skin cancer. The application of RCM for diagnosis of basal cell carcinoma has been reported; however, the evaluation of actinic keratoses (AKs) has only been the subject of preliminary studies.

Study Goal: The goal of this study was to evaluate the applicability of RCM in the diagnosis of AK in correlation with routine histology.