Publications by authors named "Adrienne E Pohl"
The flavivirus envelope protein is a class II fusion protein that drives flavivirus-cell membrane fusion. The membrane fusion process is triggered by the conformational change of the E protein from dimer in the virion to trimer, which involves the rearrangement of three domains, EDI, EDII, and EDIII. The movement between EDI and EDII initiates the formation of the E protein trimer.
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- The bacterium causing Legionnaires' disease uses many specialized proteins to help it reproduce within immune cells, with some of these proteins regulating others.
- One specific metaeffector, now renamed MesI (previously Lpg2505), is crucial for the bacterium's growth when paired with another effector called SidI, which disrupts protein production in host cells.
- Researchers found that MesI can inhibit SidI's interference with protein translation and discovered that SidI also has a new enzymatic function, enhancing our understanding of how this bacterium replicates intracellularly.