Publications by authors named "Adrienne Astrid Gallizzi"
Front Immunol
August 2024
Article Synopsis
- Anaphylaxis is a severe allergic reaction initiated by allergens activating B-cells, but existing understanding of its mechanisms is incomplete, prompting a review of proteomic and metabolomic studies to identify new biomarkers.
- A systematic search identified 12 relevant studies from 137 publications, which showed variations in protein expression related to neutrophil activation and platelet degranulation, along with common metabolites like arachidonic acid.
- The findings suggest that neutrophils and platelets play a greater role in anaphylaxis than previously thought, but require further research with larger human study samples to validate and potentially develop new diagnostic biomarkers.
