[The role of gallium scintigraphy in the diagnosis of sarcoidosis and in monitoring treatment effectiveness].

Sarcoidosis is an inflammatory disorder of unclear origin that can affect many organs. The hallmark of sarcoidosis is formation non-caseating epithelioid cell granulomas. The aetiology and the pathogenesis of the disease are not well understood, therefore in the absence of specific histopathology distinguishing marks the diagnosis is established by exclusion.

[Hyperinsulinemia, insulin-like growth factor-I, insulin-like growth factor-binding protein-1, and sex-hormone binding-globulin in prepubertal and pubertal girls with premature adrenarche].

Precocious adrenarche is defined as the development of pubic hair before the age of 8 years in girls and 9 years in boys. Pubarche caused premature adrenarche in girls has been considered as a normal variant of pubertal development for years. Recently, it is cleared that premature pubarche can be considered as a marker of increased risk for endocrine and metabolic abnormalities.