Nosocomial outbreak caused by disinfectant-resistant in an adult intensive care unit, Hungary, February to March 2022.

In 2022, an outbreak with severe bloodstream infections caused by occurred in an adult intensive care unit (ICU) in Hungary. Eight cases, five of whom died, were detected. Initial control measures could not stop the outbreak.

Genomic Epidemiology of C2/H30Rx and C1-M27 Subclades of ST131 Isolates from Clinical Blood Samples in Hungary.

Extended-spectrum β-lactamase-producing ST131 has become widespread worldwide. This study aims to characterize the virulome, resistome, and population structure of ST131 isolates from clinical blood samples in Hungary. A total of 30 C2/H30Rx and 33 C1-M27 ST131 isolates were selected for Illumina MiSeq sequencing and 30 isolates for MinION sequencing, followed by hybrid de novo assembly.

Transmissible silver resistance readily evolves in high-risk clone isolates of Klebsiella pneumoniae.

Silver is used extensively in both hospitals and outpatient clinics as a disinfectant coating agent on various devices. Resistance to silver was recently reported as an emerging problem in Enterobacteriaceae. Multidrug-resistant high-risk clones of Klebsiella pneumoniae are common causes of serious healthcare-associated infections worldwide posing a serious threat to patients.

Quantitative study about the role of environmental conditions in the survival capability of multidrug-resistant bacteria.

Background: Healthcare-associated infections (HAIs) caused by multidrug-resistant bacteria (MDRB) are of global concern and hospital textiles can contribute to their transmission. MDRB are able to survive on textiles for more than enough time to spread in the environment. Some studies summarized the effect of environmental factors on the duration of bacterial survival, but it remained an open question how these factors influence the quantity of surviving bacteria in a period of a few days, which is relevant from the perspective of HAIs.