Publications by authors named "Adrianus Johannes Christiaan van den Brule"
HPV Prevalence in the Dutch cervical cancer screening population (DuSC study): HPV testing using automated HC2, cobas and Aptima workflows.
Cornelis Johannes Jacobus Huijsmans Willemina Rosalia Rita Geurts-Giele Cindy Leeijen Hendrikus Lambertus Cornelius Maria Hazenberg Jenneke van Beek Adrianus Johannes Christiaan van den Brule
BMC Cancer
November 2016
Background: Primary high risk (hr)HPV screening will be introduced in The Netherlands in January 2017. Our aim was to determine the hrHPV prevalence in the Dutch cervical cancer screening population (DuSC study).
Methods: A total of 12,113 residual PreservCyt cervical samples from the Dutch population based cytology screening program were rendered anonymous, randomized and tested for hrHPV using 3 HPV assays on their respective automated platforms: QIAGEN's digene® HC2 HPV DNA Test® (HC2, signal amplification), Roche Cobas® HPV test (DNA amplification) and Hologic Aptima® HPV Test (RNA amplification).