Exercise Inhibits the Effects of Smoke-Induced COPD Involving Modulation of STAT3.

Purpose: Evaluate the participation of STAT3 in the effects of aerobic exercise (AE) in a model of smoke-induced COPD.

Methods: C57Bl/6 male mice were divided into control, Exe, COPD, and COPD+Exe groups. Smoke were administered during 90 days.

Exercise Performed Concomitantly with Particulate Matter Exposure Inhibits Lung Injury.

Air pollution is a growing problem worldwide, inducing and exacerbating several diseases. Among the several components of air pollutants, particulate matter (PM), especially thick (10-2.5 µm; PM 10) and thin (≤2.

Dendritic Cells Are Involved in the Effects of Exercise in a Model of Asthma.

Introduction: This study investigated the effects of aerobic exercise (AE) on both the maturation of dendritic cells (DC) and the activation of lymphocytes in a mouse model of chronic allergic airway inflammation.

Methods: C57BL/6 mice distributed into control, exercise, ovalbumin (OVA), and OVA + exercise groups were submitted to OVA sensitization and challenge. Treadmill training was performed for 4 wk, and mice were assessed for classical features of chronic allergic airway inflammation as well as dendritic cell activation and T-lymphocyte response.