Chemical analysis of irradiated root dentin and its interaction with resin cements.

Objectives: To investigate the chemical changes in root dentin submitted to ionizing radiation and how it affects the interaction with resin cements.

Materials And Methods: Forty human premolars were randomly divided into two groups (n = 20): non-irradiated and irradiated. They were randomly subdivided according to the type of resin cement (n = 10): conventional (RelyX ARC, 3 M ESPE) or self-adhesive (RelyX U200, 3 M ESPE).

Cell therapy stimulates bone neoformation in calvaria defects in rats subjected to local irradiation.

Background: The purpose of the study was to analyze the effect of cell therapy on the repair process in calvaria defects in rats subjected to irradiation.

Methods: Bone marrow mesenchymal cells were characterized for osteoblastic phenotype. Calvariae of male Wistar rats were irradiated (20 Gy) and, after 4 weeks, osteoblastic cells were placed in surgically created defects in irradiated (IRC) and control animals (CC), paired with untreated irradiated (IR) and control (C) animals.