vibro-acoustography characterization of osteoporosis in an experimental mice model.

Background: Osteoporosis is a highly prevalent multifactorial osteometabolic disease, classically diagnosed, , by dual energy X-ray absorptiometry (DXA). This study evaluated osteoporosis, , using vibro-acoustography (VA), an elastographic technique based on ultrasound radiation force.

Methods: Three groups of mice femurs were used: (I) control group (CG), (II) osteoporosis group (OG) and (III) treated osteoporosis group (TOG), in which the animals received pamidronate, an antiresorptive drug.

Boron supplementation improves bone health of non-obese diabetic mice.

Diabetes Mellitus is a condition that predisposes a higher risk for the development of osteoporosis. The objective of this study was to investigate the influence of boron supplementation on bone microstructure and strength in control and non-obese diabetic mice for 30days. The animals were supplemented with 40μg/0,5ml of boron solution and controls received 0,5ml of distilled water daily.