Publications by authors named "Adrianna Machinena"
Article Synopsis
- Food protein-induced enterocolitis syndrome (FPIES) is a food allergy mostly affecting infants, characterized by severe vomiting and shock, and its diagnosis can be delayed due to unclear genetic markers.
- This study analyzed the genomes of 41 FPIES patients, identifying significant genetic variants linked to the syndrome, including genes that may influence immune response and gut health.
- The results enhance understanding of FPIES' genetic basis and could pave the way for better diagnosis, treatment, and prevention strategies in the future.
Background: Chronic urticaria (CU) is defined as the occurrence of wheals/angioedema for ≥6 consecutive weeks. Until now, guidelines and publications addressing CU have focused mainly on adults. As a result, evidence and guidance in the pediatric population are scarce.
View Article and Find Full Text PDFSafety of Food Oral Immunotherapy: What We Know, and What We Need to Learn.
Immunol Allergy Clin North Am
February 2020
Oral immunotherapy (OIT) for food allergy entails a risk of adverse reactions, including anaphylaxis. This safety concern is the major barrier for OIT to become a therapeutic option in clinical practice. The high heterogeneity in safety reporting of OIT studies prevents setting the safety profile accurately.
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