Degron Pathways and Leishmaniasis: Debating Potential Roles of spp. Proteases Activity on Guiding Hosts Immune Response and Their Relevance to the Development of Vaccines.

Degrons are short peptide sequences that signalize target sites for protein degradation by proteases. Herein, we bring forth the discussion on degrons present in proteins related to the immune system of that are potential targets for cysteine and serine proteases of spp. and their possible roles on host immune regulation by parasites.