Publications by authors named "Adriana Vazquez-Medina"
Article Synopsis
- - Nimodipine is the only FDA-approved drug for neuroprotection in patients with aneurysmal subarachnoid hemorrhage (aSAH) and has shown clinical benefits in randomized trials, though these were conducted before advancements in precision medicine.
- - The standard dosage of nimodipine (60 mg every 4 hours) often leads to systemic arterial hypotension in up to 78% of patients, which can compromise its effectiveness and cerebral blood flow, especially during vasospasm.
- - A study involving 150 aSAH patients explored the effects of nimodipine dose adjustments on clinical outcomes, highlighting the importance of pharmacogenomics for personalized dosing strategies in future treatments.
Objective: To report the operative outcomes after treating vertebral osteomyelitis patients with an anterior cervical corpectomy and fusion procedure using recombinant human bone morphogenetic protein-2 (rhBMP-2) as graft material.
Methods: A retrospective review of electronic medical records of 26 adult patients who underwent an anterior cervical corpectomy and fusion procedure for cervical osteomyelitis using rhBMP-2 at the University of Puerto Rico University District Hospital was performed. Indication, preoperative laboratory results, levels of corpectomy, preoperative American Spinal Injury Association Impairment Scale (ASIA) score, complications, fusion evaluation at 12 months, and ASIA score at 12 months were reviewed.
The aim of this report is to describe TransOrbital NeuroEndoscopic Surgery (TONES) as a safe alternative for obtaining a cavernous sinus (CS) biopsy. We describe this technique in a patient with a diffuse large B cell lymphoma mimicking Tolosa-Hunt's syndrome. Articles were gathered querying PubMed, Embase, and Scopus databases with terms related to a "transorbital neuroendoscopic approach.
View Article and Find Full Text PDFThe heme protein cytochrome c (Cyt c) plays pivotal roles in cellular life and death processes. In the respiratory chain of mitochondria, it serves as an electron transfer protein, contributing to the proliferation of healthy cells. In the cell cytoplasm, it activates intrinsic apoptosis to terminate damaged cells.
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